Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 17/20 | 0.66 |
| ▸ | BCHE | P06276 | 16/20 | 0.66 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543965 | 0.98 | ACHE (0.66) | ACHEBCHEAPPMAOBCHRM2 | |
| Memoquin SCHEMBL4365745 | 0.95 | ACHE (0.73) | ACHEBCHEAPPMAOBCHRM2 | |
| Memoquin SCHEMBL29416823 | 0.95 | ACHE (0.73) | ACHEBCHEAPPMAOBCHRM2 | |
| SCHEMBL4373839 | 0.95 | ACHE (0.73) | ACHEBCHEAPPMAOBCHRM2 | |
| SCHEMBL13876832 | 0.95 | ACHE (0.73) | ACHEBCHEAPPMAOBCHRM2 | |
| SCHEMBL13876830 | 0.94 | ACHE (0.71) | ACHEBCHEAPPMAOBCHRM2 | |
| SCHEMBL4370571 | 0.90 | BCHE (0.65) | ACHEBCHEAPPMAOB | |
| SCHEMBL4372983 | 0.90 | ACHE (0.66) | ACHEBCHEAPPMAOBCHRM2 | |
| SCHEMBL13890778 | 0.89 | BCHE (0.65) | ACHEBCHEAPPMAOB | |
| SCHEMBL13706588 | 0.87 | ACHE (0.67) | ACHEBCHEAPPMAOBCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034457-A1 | ORGANIC COMPOUNDS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES, USES AND METHODS FOR THE PREPARATION THEREOF | ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA (IT) | 2009-03-19 | — | — | WO | disclosed |