SCHEMBL4371935

SCHEMBL4371935

Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](N)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 1/20 0.71
▸ KRAS P01116 4/20 0.67
▸ NT5E P21589 1/20 0.66
▸ FUT5 Q11128 1/20 0.66
▸ P2RY6 Q15077 2/20 0.62
▸ P2RY2 P41231 1/20 0.62
▸ P2RY4 P51582 1/20 0.62
▸ P2RX3 P56373 3/20 0.61
▸ P2RX1 P51575 2/20 0.60
▸ P2RX2 Q9UBL9 1/20 0.60
▸ ENPP1 P22413 2/20 0.59
▸ P2RY1 P47900 2/20 0.59
▸ P2RY11 Q96G91 1/20 0.59
▸ P2RX4 Q99571 1/20 0.59
▸ POLB P06746 1/20 0.58
▸ DCPS Q96C86 1/20 0.58
▸ P2RY12 Q9H244 1/20 0.57
▸ IMPDH2 P12268 4/20 0.56
▸ IMPDH1 P20839 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850287 0.93 TGM2 (0.71) TGM2KRASNT5EFUT5P2RY6
SCHEMBL15747234 0.93 TGM2 (0.71) TGM2KRASNT5EFUT5P2RY6
SCHEMBL4379787 0.93 TGM2 (0.71) TGM2KRASNT5EFUT5P2RY6
SCHEMBL17160788 0.93 TGM2 (0.71) TGM2KRASNT5EFUT5P2RY6
Gtp SCHEMBL18784960 0.93 TGM2 (0.81) TGM2KRASNT5EFUT5P2RY6
Gtp SCHEMBL96708 0.93 TGM2 (0.81) TGM2KRASNT5EFUT5P2RY6
SCHEMBL376140 0.93 TGM2 (0.81) TGM2KRASNT5EFUT5P2RY6
Guanosine Triphosphate SCHEMBL44408 0.93 TGM2 (0.81) TGM2KRASNT5EFUT5P2RY6
Gtp SCHEMBL18271799 0.93 TGM2 (0.81) TGM2KRASNT5EFUT5P2RY6
SCHEMBL19691775 0.93 TGM2 (0.81) TGM2KRASNT5EFUT5P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115380-B2 Kits and methods for generating 5′ capped RNA CELLSCRIPT, LLC (US) 2015-08-25 — — US disclosed
US-20150191760-A1 KITS AND METHODS FOR GENERATING 5' CAPPED RNA CELLSCRIPT LLC (US) 2015-07-09 — — US disclosed
US-9005930-B2 Kits and methods for generating 5′ capped RNA CELLSCRIPT, LLC (US) 2015-04-14 — — US disclosed
US-20140363876-A1 KITS AND METHODS FOR GENERATING 5' CAPPED RNA EPICENTRE TECHNOLOGIES 2014-12-11 — — US disclosed
US-8846348-B2 Kits and methods for generating 5′ capped RNA CELLSCRIPT, LLC (US) 2014-09-30 — — US disclosed
US-20140221248-A1 KITS AND METHODS FOR GENERATING 5' CAPPED RNA CELLSCRIPT, LLC (US) 2014-08-07 — — US disclosed
EP-2010659-B1 Kits and methods for generating 5' capped RNA CELLSCRIPT INC (US) 2014-06-18 — — EP disclosed
EP-2010659-A2 KITS AND METHODS FOR GENERATING 5' CAPPED RNA Epicentre Technologies (US) 2009-01-07 — — EP disclosed
US-20070281336-A1 Kits and methods for generating 5' capped RNA EPICENTRE TECHNOLOGIES (US) 2007-12-06 — — US disclosed
WO-2007120863-A2 KITS AND METHODS FOR GENERATING 5' CAPPED RNA EPICENTRE TECHNOLOGIES (US) 2007-10-25 — — WO disclosed
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