Gtp

Gtp

SCHEMBL96708

Nc1nc2c(ncn2[C@@H]2O[C@@H](CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)[C@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.81
NT5E P21589 1/20 0.76
KRAS P01116 2/20 0.76
FUT5 Q11128 1/20 0.75
P2RX3 P56373 2/20 0.71
P2RY6 Q15077 2/20 0.71
P2RY2 P41231 1/20 0.71
P2RY4 P51582 1/20 0.71
P2RY1 P47900 4/20 0.68
ENPP1 P22413 2/20 0.68
P2RX1 P51575 1/20 0.68
P2RY11 Q96G91 1/20 0.68
P2RX4 Q99571 1/20 0.68
P2RY12 Q9H244 1/20 0.66
IMPDH2 P12268 5/20 0.65
IMPDH1 P20839 1/20 0.65
DCPS Q96C86 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gtp SCHEMBL18271799 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
Gtp SCHEMBL3333959 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
SCHEMBL376140 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
Gtp SCHEMBL18784960 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
SCHEMBL376139 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
SCHEMBL1304258 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
SCHEMBL19691775 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
SCHEMBL2593095 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
Gtp SCHEMBL5809658 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3
Gtp SCHEMBL17367368 1.00 TGM2 (0.81) TGM2NT5EKRASFUT5P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260061039-A1 PRODUCTION OF 2-3-CYCLIC GMP-AMP (cGAMP) AND METHOD OF USE THEREOF UNIV COLORADO REGENTS (US) 2026-03-05 US claimed
EP-3752610-B1 POLYRIBONUCLEOTIDE CONTAINING DEUTERATED NUCLEOTIDES ETHRIS GMBH (DE) 2026-01-28 EP claimed
US-20250378906-A1 METHODS AND ARRANGEMENTS FOR INTERACTIVE SIMULATION OF XRNA PRODUCTION ARRANTA BIO HOLDINGS LLC (US) 2025-12-11 US claimed
US-12492234-B2 Fiber assembly and use thereof KYOTO UNIVERSITY (JP) 2025-12-09 US claimed
US-20250295658-A1 ANTIPARASITIC AGENTS AND METHODS WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH 2025-09-25 US claimed
US-20250277180-A1 APPARATUS, SYSTEMS AND METHODS FOR CONTINUOUS RNA MANUFACTURING MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2025-09-04 US claimed
EP-4581169-A2 METHODS OF ENZYMATICALLY REPAIRING CLEAVED RNAS AND DETECTING THEREOF The Johns Hopkins University (US) 2025-07-09 EP claimed
US-12280105-B2 Compositions and methods of mRNA vaccines against novel coronavirus infection RNAimmune, Inc. (US) 2025-04-22 US claimed
US-12280104-B2 Composition and methods for MRNA vaccines against novel omicron coronavirus infections RNAimmune, Inc. (US) 2025-04-22 US claimed
EP-4486909-A2 RNA MOLECULE Imperial College Innovations Limited (GB) 2025-01-08 EP claimed
WO-2001077366-A1 POSITIVE SELECTION METHOD, COMPOUNDS, HOST CELLS AND USES THEREOF CUBIST PHARMACEUTICALS, INC. (US) 2001-10-18 WO claimed
EP-1025115-A1 NOVEL NUCLEOSIDE OR NUCLEOTIDE FLUORESCENT CONJUGATES, PREPARATION METHOD AND USES CIS BIO INTERNATIONAL (FR) 2000-08-09 EP claimed
WO-1999018114-A1 NOVEL NUCLEOSIDE OR NUCLEOTIDE FLUORESCENT CONJUGATES, PREPARATION METHOD AND USES CIS BIO INTERNATIONAL (FR) 1999-04-15 WO claimed
WO-1996011398-A1 PROCESS FOR ASSESSING TUBULIN PROTEIN POLYMERIZATION MERCK & CO., INC. (US) 1996-04-18 WO claimed
WO-1995024497-A2 ENZYMATIC PREPARATION OF POLYSACCHARIDES FIDIA ADVANCED BIOPOLYMERS S.R.L. (IT) 1995-09-14 WO claimed
EP-0090417-B1 PROCESS FOR PRODUCING 3'-DEOXYGUANOSINE Yamasa Shoyu Kabushiki Kaisha (JP) 1989-03-01 EP claimed
US-4594321-A Reacting guanine derivative with phosphate YAMASA SHOYU KABUSHIKI KAISHA (JP) 1986-06-10 US claimed
US-4594320-A Reacting guanine derivative with phosphate compound YAMASA SHOYU KABUSHIKI KAISHA (JP) 1986-06-10 US claimed
US-4577012-A ABSORPTION ON ACTIVATED CARBON, ELUTION WITH ALKALI HYDROXIDE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-03-18 US claimed
EP-0090417-A2 Process for producing 3'-deoxyguanosine Yamasa Shoyu Kabushiki Kaisha (JP) 1983-10-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061039-A1 PRODUCTION OF 2-3-CYCLIC GMP-AMP (cGAMP) AND METHOD OF USE THEREOF CGAS, PDE11A, PDE3B TGM2 853/4885NT5E 88/4885KRAS 4776/4885
US-12280104-B2 Composition and methods for MRNA vaccines against novel omicron coronavirus infections RBM22, RNGTT, RBM25 TGM2 3045/4885NT5E 930/4885KRAS 1393/4885
US-12280105-B2 Compositions and methods of mRNA vaccines against novel coronavirus infection RNGTT, SARS1, ACE2 TGM2 766/4885NT5E 1065/4885KRAS 810/4885
US-20250295658-A1 ANTIPARASITIC AGENTS AND METHODS DHFR, DHODH, MTHFD1 TGM2 108/4885NT5E 402/4885KRAS 3461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.