⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306395 | 0.87 | ALDH1A1 (0.45) | — | |
| SCHEMBL8058918 | 0.84 | ALDH1A1 (0.43) | — | |
| Di(Hydroxyethyl)Ether SCHEMBL10582766 | 0.81 | TSHR (0.59) | — | |
| Di(Hydroxyethyl)Ether SCHEMBL439676 | 0.81 | TSHR (0.59) | — | |
| Di(Hydroxyethyl)Ether SCHEMBL787692 | 0.81 | TSHR (0.59) | — | |
| Triethylene Glycol SCHEMBL989878 | 0.79 | KMT2A (0.61) | — | |
| Triethylene Glycol SCHEMBL10582059 | 0.79 | KMT2A (0.61) | — | |
| Triethylene Glycol SCHEMBL6292167 | 0.79 | KMT2A (0.61) | — | |
| Di(Hydroxyethyl)Ether SCHEMBL28257194 | 0.79 | TSHR (0.56) | — | |
| Tetraethylene Glycol SCHEMBL1773960 | 0.79 | KMT2A (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682093-B2 | Compositions and methods for treating or preventing metabolic syndrome disorders | CHARLES R. DREW UNIVERSITY OF MEDICINE AND SCIENCE (US) | 2017-06-20 | — | — | US | disclosed |
| WO-2017083468-A1 | REACTIVE FLAME REARDANTS FOR POLYURETHANE AND POLYISOCYANURATE FOAMS | ICL-IP AMERICA INC. (US) | 2017-05-18 | — | — | WO | disclosed |
| US-20160120890-A1 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS | CHARLES R. DREW UNIVERSITY OF MEDICINE AND SCIENCE | 2016-05-05 | — | — | US | disclosed |
| EP-2069342-A1 | 2-ARYL-6-PHENYLIMIDAZO[1,2-ALPHA]PYRIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008034974-A1 | 2-ARYL-6-PHENYLIMIDAZO[1,2-α]PYRIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2008-03-27 | — | — | WO | disclosed |
| US-20030212116-A1 | Heterocyclic imino compounds and fungicides and insecticides for agricultural and horitcultural use | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-1243580-A1 | HETEROCYCLIC IMINO COMPOUNDS AND FUNGICIDES AND INSECTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE | Nissan Chemical Industries, Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |