SCHEMBL4372159

SCHEMBL4372159

C=Cc1ccc(OCCCC[SiH](OC)OC)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNB4 P30926 2/20 0.50
CHRNA3 P32297 2/20 0.50
CHRNA7 P36544 2/20 0.50
CHRNB2 P17787 1/20 0.50
CHRNA4 P43681 1/20 0.50
AHR P35869 1/20 0.39
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
APP P05067 10/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1269642 0.84 CHRNA7 (0.51) CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4
SCHEMBL1260922 0.82 CHRNA7 (0.61) CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4
SCHEMBL2623208 0.81 CHRNB4 (0.57) CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4
SCHEMBL8754087 0.80 CHRNB2 (0.59) CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4
SCHEMBL1140632 0.80 CHRNB2 (0.59) CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4
SCHEMBL8759065 0.80 TDP1 (0.38) CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4
SCHEMBL9315817 0.80 CHRNA7 (0.49) CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4
SCHEMBL2623210 0.80 CHRNB2 (0.56) CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4
SCHEMBL10071492 0.80 CHRNB2 (0.56) CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4
SCHEMBL10071495 0.80 CHRNB2 (0.56) CHRNB4CHRNA3CHRNA7CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1383470-B1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2009-06-17 EP disclosed
EP-1383469-B1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2006-02-15 EP disclosed
EP-1383860-B1 FABRIC CARE COMPOSITIONS UNILEVER PLC (GB) 2005-10-12 EP disclosed
US-6767883-B2 Fabric care compositions UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. 2004-07-27 US disclosed
US-6696051-B2 CONTAINING CORE PARTICLES HAVING A D3,2 AVERAGE PARTICLE SIZE OF 10-700 NM, AND COATED WITH COVALENTLY BONDED SILICONE POLYMER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
US-6696050-B2 COATED PARTICLES COMPRISING (A) A SOLID CORE HAVING A D3, 2 AVERAGE PARTICLE SIZE IN THE RANGE FROM 10 TO 700 NM, AND (B) A COATING POLYMER COVALENTLY BONDED TO THE SOLID CORE; E.G., SOLID SILICA CORES AND POLYSTYRENE COATING POLYMER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
EP-1383469-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2004-01-28 EP disclosed
EP-1383468-A2 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2004-01-28 EP disclosed
EP-1383470-A2 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2004-01-28 EP disclosed
EP-1383860-A1 FABRIC CARE COMPOSITIONS Unilever Plc (GB) 2004-01-28 EP disclosed
US-20030095943-A1 Hair treatment compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-05-22 US disclosed
US-20030012757-A1 Hair treatment compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-01-16 US disclosed
US-20020192367-A1 Fabric care compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-12-19 US disclosed
WO-2002087523-A2 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
WO-2002087525-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
WO-2002088293-A1 FABRIC CARE COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
WO-2002087522-A2 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
US-5545715-A INCLUDING BROMINE-CONTAINING COPOLYMER, FLAME-RETARDING ADJUVANT, POLYSILOXANE-REINFORCED RESIN; NONDRIPPING JAPAN SYNTHETIC RUBBER CO. LTD. (JP) 1996-08-13 US disclosed
EP-0578873-B1 Flame-retardant resin composition DSM NV (NL) 1995-12-06 EP disclosed
EP-0578873-A1 Flame-retardant resin composition DSM N.V. (NL) 1994-01-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030095943-A1 Hair treatment compositions SPTLC3, HACD3, C18orf63 CHRNB4 1778/4885CHRNA3 497/4885CHRNA7 1548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.