SCHEMBL4372489

SCHEMBL4372489

Nc1ccc(-c2ccccc2)c(O)c1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 3/20 0.48
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
BACE1 P56817 1/20 0.44
ALOX5 P09917 1/20 0.43
HPGD P15428 3/20 0.43
BCL2L1 Q07817 1/20 0.43
HNF4A P41235 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CSNK1A1 P48729 2/20 0.41
CSNK1D P48730 2/20 0.41
CSNK1G1 Q9HCP0 2/20 0.41
POLB P06746 1/20 0.41
PABPC1 P11940 1/20 0.41
BLM P54132 1/20 0.41
MCL1 Q07820 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15506229 0.96 HSD17B10 (0.47) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL28318563 0.86 HSD17B10 (0.43) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL8724544 0.86 HSD17B10 (0.52) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL5595212 0.85 ALDH1A1 (0.46) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL8853081 0.84 ALDH1A1 (0.50) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL3976573 0.83 HDAC4 (0.61) ALDH1A1HSD17B10HDAC4HDAC2HDAC8
SCHEMBL27557303 0.83 HSD17B10 (0.50) ALDH1A1HSD17B10BACE1ALOX5HPGD
SCHEMBL30866155 0.82 HSD17B10 (0.52) ALDH1A1HSD17B10BACE1ALOX5CSNK1A1
SCHEMBL845162 0.82 HSD17B10 (0.52) ALDH1A1HSD17B10BACE1ALOX5CSNK1A1
SCHEMBL4647831 0.81 HDAC4 (0.54) ALDH1A1HSD17B10HDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014038867-A1 A NOVEL COMBINATION OF A HOST COMPOUND AND A DOPANT COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-03-13 WO disclosed
US-20090294298-A1 Detection of Phenols ISIS INNOVATION LIMITED (GB) 2009-12-03 US disclosed
EP-1853684-A2 METHOD FOR IMPROVING THE OXIDATIVE STABILITY OF INDUSTRIAL FLUIDS Chemtura Corporation (US) 2007-11-14 EP disclosed
WO-2006094138-A2 METHOD FOR IMPROVING THE OXIDATIVE STABILITY OF INDUSTRIAL FLUIDS CHEMTURA CORPORATION (US) 2006-09-08 WO disclosed