Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19222047 | 0.84 | NPSR1 (0.53) | NPSR1ALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL29033626 | 0.82 | NPSR1 (0.51) | NPSR1ALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL5217375 | 0.82 | NPSR1 (0.51) | NPSR1ALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL4944661 | 0.80 | NPSR1 (0.49) | NPSR1ALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL380404 | 0.80 | NPSR1 (0.49) | NPSR1ALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL2956140 | 0.79 | NPSR1 (0.60) | NPSR1ALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL8331183 | 0.79 | NPSR1 (0.60) | NPSR1ALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL419987 | 0.79 | NPSR1 (0.59) | NPSR1ALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL9336413 | 0.79 | NPSR1 (0.59) | NPSR1ALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL30486812 | 0.79 | NPSR1 (0.59) | NPSR1ALDH1A1HTTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097384-A1 | INDOZALYL SULPHONAMIDE DERIVATIVES USEFUL AS GLUCOCORTICOID MODULATORS | AstraZeneca AB (SE) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008063116-A1 | INDOZALYL SULPHONAMIDE DERIVATIVES USEFUL AS GLUCOCORTICOID MODULATORS | ASTRAZENECA AB (SE) | 2008-05-29 | — | — | WO | disclosed |
| WO-2005073389-A1 | METHOD FOR PRODUCING β-HYDROXY NITRO COMPOUNDS MADE FROM ALDEHYDES AND NITROALKANES WHILE USING A HYDROXY NITRILE LYASE | ANGEWANDTE BIOKATALYSE-KOMPETENZZENTRUM GMBH (AT) | 2005-08-11 | — | — | WO | disclosed |