Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26766431 | 0.84 | CRHR1 (0.58) | KDM4EGFERSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL18535287 | 0.83 | KDM4E (0.59) | KDM4ETDP1GFERSMN1; SMN2ALDH1A1 | |
| SCHEMBL437125 | 0.81 | NR4A2 (0.55) | NR4A2KDM4ETDP1NCF1GFER | |
| SCHEMBL29393886 | 0.80 | MAPT (0.57) | NR4A2KDM4EGFERSMN1; SMN2ALDH1A1 | |
| SCHEMBL1563307 | 0.80 | GFER (0.50) | KDM4EGFERSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11619165 | 0.80 | KDM4E (0.65) | NR4A2KDM4ETDP1NCF1GFER | |
| SCHEMBL316994 | 0.80 | MAPT (0.57) | NR4A2KDM4EGFERSMN1; SMN2ALDH1A1 | |
| SCHEMBL1564292 | 0.80 | GAA (0.54) | KDM4ETDP1GFERSMN1; SMN2ALDH1A1 | |
| SCHEMBL21000819 | 0.80 | GFER (0.60) | KDM4EGFERSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL438224 | 0.79 | NR4A2 (0.69) | NR4A2KDM4ETDP1NCF1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |