Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | MPL | P40238 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046111 | 0.82 | MAPT (0.51) | NR4A2MAPTHPGD | |
| SCHEMBL437287 | 0.81 | NR4A2 (0.61) | NR4A2KDM4ETDP1NCF1GFER | |
| SCHEMBL437914 | 0.80 | CTSS (0.41) | ADORA2AADORA1MPL | |
| SCHEMBL439735 | 0.74 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1ADORA2A | |
| SCHEMBL438224 | 0.74 | NR4A2 (0.69) | NR4A2KDM4ETDP1NCF1ALDH1A1 | |
| SCHEMBL16106553 | 0.73 | MEN1 (0.54) | KDM4ELMNAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL439824 | 0.71 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1ADORA1 | |
| SCHEMBL438980 | 0.71 | NR4A2 (1.00) | NR4A2KDM4ETDP1NCF1ALDH1A1 | |
| SCHEMBL5243405 | 0.71 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1ALDH1A1 | |
| SCHEMBL3954235 | 0.71 | ADORA2A (0.47) | KDM4ETDP1ADORA2AALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |