Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373152 | 1.00 | PTGER4 (0.38) | PTGER4PTGER3PTGER2CHRM2CHRM4 | |
| SCHEMBL4373157 | 1.00 | PTGER4 (0.38) | PTGER4PTGER3PTGER2CHRM2CHRM4 | |
| SCHEMBL14277404 | 0.97 | PTGER4 (0.36) | PTGER4PTGER3PTGER2CHRM2CHRM4 | |
| SCHEMBL4373151 | 0.91 | PTGER4 (0.39) | PTGER4PTGER2CHRM2CHRM4CHRM5 | |
| SCHEMBL4373158 | 0.91 | PTGER4 (0.39) | PTGER4PTGER2CHRM2CHRM4CHRM5 | |
| SCHEMBL4373155 | 0.91 | PTGER4 (0.39) | PTGER4PTGER2CHRM2CHRM4CHRM5 | |
| SCHEMBL4389493 | 0.90 | PTGER4 (0.38) | PTGER4PTGER2 | |
| SCHEMBL4389496 | 0.90 | PTGER4 (0.38) | PTGER4PTGER2 | |
| SCHEMBL4389499 | 0.90 | PTGER4 (0.38) | PTGER4PTGER2 | |
| SCHEMBL4375101 | 0.90 | PTGER4 (0.36) | PTGER4PTGER3PTGER2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817033-B1 | TREATMENT OF INFLAMMATORY BOWEL DISEASE | ALLERGAN INC (US) | 2009-11-18 | — | — | EP | disclosed |
| US-7326716-B2 | Treatment of inflammatory bowel disease | ALLERGAN, INC. (US) | 2008-02-05 | — | — | US | disclosed |
| US-7179820-B2 | Piperidinyl prostaglandin E analogs | ALLERGAN, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| US-20050171062-A1 | Treatment of inflammatory bowel disease | ALLERGAN, INC. (US) | 2005-08-04 | — | — | US | disclosed |
| US-20040248854-A1 | Piperidinyl prostaglandin E analogs | ALLERGAN, INC. | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171062-A1 | Treatment of inflammatory bowel disease | SLC10A2, GUCY1B1, PTGER1 | PTGER4 18/4885PTGER3 8/4885PTGER2 33/4885 |
| US-20040248854-A1 | Piperidinyl prostaglandin E analogs | PTGIR, PTGER1, PTGS1 | PTGER4 14/4885PTGER3 5/4885PTGER2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.