SCHEMBL4373387

SCHEMBL4373387

O=C(O)C=CCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C=CC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.33
GABRR2 P28476 2/20 0.33
BLM P54132 2/20 0.33
GABRR3 A8MPY1 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
APEX1 P27695 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4373384 1.00 GABRR1 (0.33) GABRR1GABRR2BLMGABRR3LMNA
SCHEMBL6036567 0.84 THRB (0.38) GABRR1GABRR2BLMGABRR3LMNA
SCHEMBL6036625 0.84 THRB (0.38) GABRR1GABRR2BLMGABRR3LMNA
SCHEMBL5360468 0.77 TSHR (0.32) TSHR
SCHEMBL5412517 0.76 TSHR (0.31) TSHR
SCHEMBL4340454 0.76 TSHR (0.31) TSHR
SCHEMBL25332670 0.75 TSHR (0.39) GABRR1GABRR2BLMGABRR3LMNA
SCHEMBL2498836 0.74 TSHR (0.42) GABRR1GABRR2BLMGABRR3LMNA
SCHEMBL2498834 0.74 TSHR (0.42) GABRR1GABRR2BLMGABRR3LMNA
SCHEMBL17812948 0.72 TSHR (0.41) GABRR1GABRR2BLMGABRR3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7625984-B2 Low shrinkage, low optical absorbance, low refractive index adhesive composition ENABLENCE TECHNOLOGIES USA INC. (CA) 2009-12-01 US disclosed
US-7390854-B2 Low shrinkage, low optical absorbance, low refractive index adhesive composition E. I. DUPONT DE NEMOURS AND COMPANY (US) 2008-06-24 US disclosed
US-20080139773-A1 LOW SHRINKAGE, LOW OPTICAL ABSORBANCE, LOW REFRACTIVE INDEX ADHESIVE COMPOSITION ENABLENCE TECHNOLOGIES USA INC. (CA) 2008-06-12 US disclosed
US-20060099426-A1 Low shrinkage, low optical absorbance, low refractive index adhesive composition ENABLENCE TECHNOLOGIES USA INC. (CA) 2006-05-11 US disclosed