Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373788 | 1.00 | GAA (0.51) | GAANPSR1F2PLGPRSS1 | |
| SCHEMBL4540564 | 0.90 | F2 (0.45) | GAANPSR1F2PLGPRSS1 | |
| SCHEMBL4540567 | 0.90 | F2 (0.45) | GAANPSR1F2PLGPRSS1 | |
| SCHEMBL4741524 | 0.89 | F2 (0.52) | NPSR1F2PLGPRSS1MAPT | |
| SCHEMBL4799775 | 0.89 | F2 (0.52) | NPSR1F2PLGPRSS1MAPT | |
| SCHEMBL4379511 | 0.84 | KDM4E (0.45) | GAANPSR1F2PLGPRSS1 | |
| SCHEMBL4373468 | 0.83 | MAPT (0.59) | GAANPSR1MAPTPOLBLMNA | |
| SCHEMBL11550281 | 0.83 | GAA (0.70) | GAANPSR1MAPTPOLBLMNA | |
| SCHEMBL15000395 | 0.81 | TP53 (0.51) | GAAMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4786981 | 0.80 | F2 (0.51) | F2PLGPRSS1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118747-A1 | NOVEL HYDROXY FUNCTIONALIZED 1, 2, 4-TRIOXANES AS ANTIMALARIAL AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-10-01 | — | — | WO | disclosed |