Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 4/20 | 0.49 |
| ▸ | BCR | P11274 | 3/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13615433 | 0.81 | MKNK1 (0.54) | TNIKABL1MKNK1MKNK2CYP2A6 | |
| SCHEMBL22628286 | 0.76 | ABL1 (0.70) | KITABL1BCRPRKCAPDGFRB | |
| SCHEMBL14506746 | 0.76 | MKNK1 (0.61) | ABL1MKNK1MKNK2CYP2A6RET | |
| SCHEMBL12217607 | 0.74 | MKNK1 (0.60) | ABL1MKNK1MKNK2CYP2A6RET | |
| SCHEMBL3860532 | 0.74 | ABL1 (0.83) | KITABL1BCRPRKCARET | |
| SCHEMBL17666287 | 0.74 | RAPGEF4 (0.55) | KDRNPC1ALDH1A1CYP1A2 | |
| SCHEMBL13036623 | 0.73 | CYP2A6 (0.62) | MKNK1MKNK2CYP2A6SLC2A1ALDH1A1 | |
| SCHEMBL19575436 | 0.72 | ABL1 (0.62) | KITABL1BCRPRKCAPDGFRB | |
| SCHEMBL22793758 | 0.72 | ABL1 (0.70) | KITABL1BCRMKNK1MKNK2 | |
| SCHEMBL30921131 | 0.72 | ABL1 (0.58) | KITABL1BCRMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | disclosed |