Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373762 | 0.82 | SLC6A4 (0.41) | SLC6A2SLC6A4OPRM1MEN1KMT2A | |
| SCHEMBL4375443 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4OPRM1MEN1KMT2A | |
| SCHEMBL4370360 | 0.74 | SLC6A2 (0.48) | SLC6A2SLC6A4OPRM1MEN1KMT2A | |
| SCHEMBL4372256 | 0.70 | OPRK1 (0.41) | SLC6A2SLC6A4OPRM1MEN1KMT2A | |
| SCHEMBL4372937 | 0.70 | SLC6A4 (0.52) | SLC6A2SLC6A4OPRM1MEN1KMT2A | |
| SCHEMBL4369264 | 0.70 | SMN1; SMN2 (0.42) | SLC6A2SLC6A4OPRM1MEN1KMT2A | |
| SCHEMBL4369347 | 0.69 | SLC6A2 (0.48) | SLC6A2SLC6A4OPRM1MEN1KMT2A | |
| SCHEMBL4372403 | 0.68 | AGER (0.39) | SLC6A2SLC6A4OPRM1MEN1KMT2A | |
| SCHEMBL4370231 | 0.67 | SLC6A2 (0.46) | SLC6A2SLC6A4OPRM1MEN1KMT2A | |
| SCHEMBL4370558 | 0.67 | SLC6A4 (0.36) | SLC6A2SLC6A4OPRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322592-B2 | SUBSTITUTED 1-AMINOBUTAN-3-OL DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-06-17 | — | — | EP | claimed |
| EP-1322592-B1 | SUBSTITUTED 1-AMINOBUTAN-3-OL DERIVATIVES | GRUENENTHAL GMBH (DE) | 2004-07-28 | — | — | EP | claimed |