Carbromal

Carbromal

SCHEMBL4373776

CCC(Br)(CC)C(=O)NC(N)=O.CCCCCCCCCCCC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 2/20 0.41
POLB P06746 1/20 0.41
NAAA Q02083 3/20 0.40
MMP1 P03956 1/20 0.40
MMP9 P14780 1/20 0.40
MMP13 P45452 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
NCOR2 Q9Y618 1/20 0.40
GAA P10253 1/20 0.39
EPHX1 P07099 3/20 0.38
EPHX2 P34913 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38
ALOX15 P16050 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbromal SCHEMBL4373766 1.00 SOAT1 (0.41) SOAT1POLBNAAAMMP1MMP9
Carbromal SCHEMBL6907293 0.93 SMN1; SMN2 (0.40) POLBMMP13HDAC3HDAC1HDAC2
Carbromal SCHEMBL9329686 0.91 SMN1; SMN2 (0.39) MMP13HDAC3HDAC1HDAC2HDAC8
Carbromal SCHEMBL11407016 0.91 SMN1; SMN2 (0.39) MMP13HDAC3HDAC1HDAC2HDAC8
Carbromal SCHEMBL441386 0.88 EPHX1 (0.38) SOAT1EPHX1ALDH1A1
Carbromal SCHEMBL3916217 0.88 EPHX1 (0.38) SOAT1EPHX1ALDH1A1
Carbromal SCHEMBL443316 0.88 EPHX1 (0.38) SOAT1EPHX1ALDH1A1
Carbromal SCHEMBL22042312 0.88 EPHX1 (0.38) SOAT1EPHX1ALDH1A1
Tridecane SCHEMBL22325584 0.88 EPHX1 (0.38) SOAT1EPHX1ALDH1A1
Carbromal SCHEMBL8953401 0.88 EPHX1 (0.38) SOAT1EPHX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1116751-B1 POLYCARBONATE RESIN COMPOSITION, OPTICAL RECORDING MEDIUM, AND SUBSTRATE THEREFOR TEIJIN LTD (JP) 2009-07-29 EP disclosed
US-6407199-B1 MIXTURE OF AROMATIC POLYCARBONATE AND CYCLIC CARBONATE COMPOUND; HEAT RESISTANCE TEIJIN LIMITED (JP) 2002-06-18 US disclosed
EP-1116751-A1 POLYCARBONATE RESIN COMPOSITION, OPTICAL RECORDING MEDIUM, AND SUBSTRATE THEREFOR TEIJIN LIMITED (JP) 2001-07-18 EP disclosed