Carbromal

Carbromal

SCHEMBL6907293

CCC(Br)(CC)C(=O)NC(N)=O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
MAPT P10636 2/20 0.40
NR3C1 P04150 2/20 0.39
RIPK1 Q13546 1/20 0.38
HPGD P15428 2/20 0.38
SLC6A2 P23975 1/20 0.37
MMP12 P39900 1/20 0.37
MMP13 P45452 1/20 0.37
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36
PTPN1 P18031 2/20 0.36
GSK3B P49841 1/20 0.36
PTPN11 Q06124 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbromal SCHEMBL11407016 0.98 SMN1; SMN2 (0.39) SMN1; SMN2L3MBTL1MAPTNR3C1RIPK1
Carbromal SCHEMBL9329686 0.98 SMN1; SMN2 (0.39) SMN1; SMN2L3MBTL1MAPTNR3C1RIPK1
Carbromal SCHEMBL4373776 0.93 SOAT1 (0.41) MMP13ALDH1A1GAAHTTHDAC3
Carbromal SCHEMBL4373766 0.93 SOAT1 (0.41) MMP13ALDH1A1GAAHTTHDAC3
Carbromal SCHEMBL8536554 0.89 CRBN (0.36) NR3C1RIPK1HDAC3HDAC4HDAC1
Carbromal SCHEMBL11576940 0.89 KMO (0.46) SMN1; SMN2ALDH1A1
Carbromal SCHEMBL5473912 0.89 NR3C1 (0.38) L3MBTL1MAPTNR3C1RIPK1ALDH1A1
Carbromal SCHEMBL2139358 0.88 NR3C1 (0.40) NR3C1RIPK1ALDH1A1GAAHDAC3
Carbromal SCHEMBL6249616 0.88 CRBN (0.37) MAPTNR3C1RIPK1
Diphenylamine SCHEMBL10526515 0.87 MAPT (0.49) MAPTNR3C1HPGDALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113049699-B Method for detecting biphenyl anhydride and related substances thereof and application 北京鑫开元医药科技有限公司 2022-09-30 CN claimed
CN-111875787-B High-heat-resistance degradable copolyester and preparation method thereof 浙江恒逸石化研究院有限公司 2022-07-08 CN claimed
CN-114573956-A Preparation method of nano magnesium hydroxide modified degradable copolyester 浙江恒逸石化研究院有限公司 2022-06-03 CN claimed
CN-108428841-B Cellulose nanofibril/metal organic framework composite lithium ion battery diaphragm and preparation method thereof 中国科学院青岛生物能源与过程研究所 2021-01-29 CN claimed
CN-118290389-A Preparation method of bicyclo-ethanol 安徽艾立德制药有限公司 2024-07-05 CN disclosed
CN-113049699-B Method for detecting biphenyl anhydride and related substances thereof and application 北京鑫开元医药科技有限公司 2022-09-30 CN disclosed
CN-114573956-A Preparation method of nano magnesium hydroxide modified degradable copolyester 浙江恒逸石化研究院有限公司 2022-06-03 CN disclosed
CN-113049699-A Method for detecting biphenyl anhydride and related substances thereof and application 北京鑫开元医药科技有限公司 2021-06-29 CN disclosed
CN-108428841-B Cellulose nanofibril/metal organic framework composite lithium ion battery diaphragm and preparation method thereof 中国科学院青岛生物能源与过程研究所 2021-01-29 CN disclosed
US-9464166-B2 Production and use of 3,4' and 4,4'-dimethylbiphenyl isomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-10-11 US disclosed
WO-2015112252-A1 PRODUCTION AND USE OF 3,4' AND 4,4'-DIMETHYLBIPHENYL ISOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-07-30 WO disclosed
US-20150080545-A1 Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers EXXONMOBIL CHEMICAL PATENTS INC. 2015-03-19 US disclosed
US-20150080546-A1 Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers EXXONMOBIL CHEMICAL PATENTS INC. 2015-03-19 US disclosed
CN-103724317-A Method adopting bifendate to prepare bicyclol UNIV NORTHWEST NORMAL 2014-04-16 CN disclosed
US-20040147655-A1 Aromatic polycarbonate resin composition TEIJIN LIMITED (JP) 2004-07-29 US disclosed
US-6156874-A Multidimensionally crosslinkable rigid-rod benzobisazole polymer fibers GEORGIA TECH RESEARCH CORP. (US) 2000-12-05 US disclosed
US-4582925-A Tetramethylbiphenylcarboxylic acids and derivatives thereof STANDARD OIL COMPANY (INDIANA) (US) 1986-04-15 US disclosed
US-4288588-A OXIDATION OF POLYMESITYLS; USEFUL IN POLYAMIDES AND PLASTICIZERS FOR PVC STANDARD OIL COMPANY (INDIANA) (US) 1981-09-08 US disclosed
US-4154922-A PLASTICIZERS FOR PVC STANDARD OIL COMPANY (INDIANA) (US) 1979-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150080546-A1 Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers CYP4B1, HPD, DDT SMN1; SMN2 4329/4885L3MBTL1 1160/4885MAPT 4197/4885
US-20150080545-A1 Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers CYP4B1, HPD, DDT SMN1; SMN2 4329/4885L3MBTL1 1160/4885MAPT 4197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.