Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.46 |
| ▸ | TNKS | O95271 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365201 | 0.95 | ALDH1A1 (0.46) | IP6K1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL4364496 | 0.86 | IP6K1 (0.47) | IP6K1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL4377425 | 0.81 | ALDH1A1 (0.46) | IP6K1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29800566 | 0.78 | TNKS (0.48) | IP6K1ALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL23316383 | 0.78 | TNKS (0.48) | IP6K1ALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL4368274 | 0.77 | KDM4E (0.62) | IP6K1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29800672 | 0.77 | TNKS (0.47) | IP6K1ALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL23316356 | 0.77 | TNKS (0.47) | IP6K1ALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL20511901 | 0.76 | KDM4E (0.63) | IP6K1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL23316396 | 0.76 | TNKS (0.44) | IP6K1ALDH1A1MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046536-A1 | HALOGENATED QUINAZOLINYL NITROFURANS AS ANTIBACTERIAL AGENTS | ULYSSES PHARMACEUTICAL PRODUCTS, INC. (CA) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009046536-A1 | HALOGENATED QUINAZOLINYL NITROFURANS AS ANTIBACTERIAL AGENTS | ULYSSES PHARMACEUTICAL PRODUCTS, INC. (CA) | 2009-04-16 | — | — | WO | disclosed |
| US-20080146562-A1 | HALOGENATED QUINAZOLINYL NITROFURANS AS ANTIBACTERIAL AGENTS | ULYSSES PHARMACEUTICAL PRODUCTS INC., | 2008-06-19 | — | — | US | disclosed |
| US-20080146562-A1 | HALOGENATED QUINAZOLINYL NITROFURANS AS ANTIBACTERIAL AGENTS | ULYSSES PHARMACEUTICAL PRODUCTS INC., | 2008-06-19 | — | — | US | disclosed |
| US-20080146562-A1 | HALOGENATED QUINAZOLINYL NITROFURANS AS ANTIBACTERIAL AGENTS | ULYSSES PHARMACEUTICAL PRODUCTS INC., | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146562-A1 | HALOGENATED QUINAZOLINYL NITROFURANS AS ANTIBACTERIAL AGENTS | HRH3, HRH1, NQO2 | IP6K1 4784/4885ALDH1A1 1414/4885MAPT 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.