Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 7/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.36 |
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372545 | 1.00 | CNR1 (0.48) | CNR1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL4367965 | 0.91 | CNR1 (0.59) | CNR1CNR2CRHR1 | |
| SCHEMBL4371187 | 0.90 | CNR1 (0.48) | CNR1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL4371310 | 0.90 | CNR1 (0.48) | CNR1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL4371181 | 0.90 | CNR1 (0.48) | CNR1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL4368677 | 0.88 | ALDH1A1 (0.42) | CNR1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL4369414 | 0.84 | CNR1 (0.42) | CNR1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL3919720 | 0.83 | CNR1 (0.64) | CNR1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL3929740 | 0.83 | CNR1 (0.66) | CNR1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL4372526 | 0.80 | CNR1 (0.59) | CNR1LMNAMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |