Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466150 | 0.85 | NR4A2 (0.49) | NR4A2SOS2CCR1FERMT2CYP1A2 | |
| SCHEMBL902310 | 0.84 | FERMT2 (0.56) | NR4A2SOS2CHRM2CHRM4CHRM5 | |
| SCHEMBL4367045 | 0.83 | FERMT2 (0.56) | NR4A2SOS2CHRM2CHRM4CHRM5 | |
| SCHEMBL4365534 | 0.82 | FERMT2 (0.55) | NR4A2SOS2TDP1PRNPCCR1 | |
| SCHEMBL4374938 | 0.81 | CCR1 (0.49) | NR4A2SOS2CHRM2CHRM4CHRM5 | |
| SCHEMBL6661654 | 0.81 | NR4A2 (0.50) | NR4A2SOS2CHRM2CHRM4CHRM5 | |
| SCHEMBL29625389 | 0.81 | NR4A2 (0.50) | NR4A2SOS2CHRM2CHRM4CHRM5 | |
| SCHEMBL5275609 | 0.78 | NR4A2 (0.56) | NR4A2SOS2TDP1PRNPCCR1 | |
| SCHEMBL8539820 | 0.78 | NR4A2 (0.47) | NR4A2SOS2CHRM2CHRM4CHRM5 | |
| SCHEMBL4377782 | 0.75 | CHRM2 (0.52) | NR4A2CHRM2CHRM4CHRM5ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009148659-A2 | ANTIMALARIAL QUINOLINES AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2009-12-10 | — | — | WO | disclosed |