Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.50 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367045 | 0.96 | FERMT2 (0.56) | FERMT2NR4A2SOS2CYP1A2CCR1 | |
| SCHEMBL4365534 | 0.93 | FERMT2 (0.55) | FERMT2NR4A2SOS2CYP1A2CCR1 | |
| SCHEMBL5275609 | 0.85 | NR4A2 (0.56) | FERMT2NR4A2SOS2CYP1A2CCR1 | |
| SCHEMBL4374933 | 0.84 | NR4A2 (0.46) | FERMT2NR4A2SOS2CYP1A2CCR1 | |
| SCHEMBL6661654 | 0.83 | NR4A2 (0.50) | FERMT2NR4A2SOS2CYP1A2CCR1 | |
| SCHEMBL29625389 | 0.83 | NR4A2 (0.50) | FERMT2NR4A2SOS2CYP1A2CCR1 | |
| SCHEMBL4374938 | 0.81 | CCR1 (0.49) | FERMT2NR4A2SOS2CYP1A2CCR1 | |
| SCHEMBL6661655 | 0.81 | FERMT2 (0.53) | FERMT2NR4A2SOS2CYP1A2CCR1 | |
| SCHEMBL15924403 | 0.79 | LOXL2 (0.50) | FERMT2CYP1A2CYP3A4TDP1CYP2D6 | |
| SCHEMBL4374931 | 0.77 | FERMT2 (0.52) | FERMT2NR4A2SOS2CYP1A2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264810-A1 | COMPOSITIONS AND METHODS FOR ENHANCING CELLULAR UPTAKE AND INTRACELLULAR DELIVERY OF LIPID PARTICLES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-10-18 | — | — | US | disclosed |
| WO-2012041493-A1 | AMINOQUINOLINIUM SALTS, METHODS OF THEIR PRODUCTION AND THEIR USE AS ACTIVE AGENTS FOR BIOTECHNOLOGICAL AND MEDICAL APPLICATIONS AGAINST BINARY TOXINS | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2012-04-05 | — | — | WO | disclosed |
| WO-2011036557-A1 | COMPOSITIONS AND METHODS FOR ENHANCING CELLULAR UPTAKE AND INTRACELLULAR DELIVERY OF LIPID PARTICLES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264810-A1 | COMPOSITIONS AND METHODS FOR ENHANCING CELLULAR UPTAKE AND INTRACELLULAR DELIVERY OF LIPID PARTICLES | NPC1L1, ABCB4, NPC1 | FERMT2 1125/4885NR4A2 2060/4885SOS2 4063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.