Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 5/20 | 0.61 |
| ▸ | CCR2 | P41597 | 9/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22003888 | 0.81 | ACLY (0.67) | ACLYCCR2PPARGPPARDPPARA | |
| SCHEMBL741459 | 0.81 | ACLY (0.64) | ACLYCCR2PPARGPPARDPPARA | |
| SCHEMBL7743563 | 0.80 | MCL1 (0.60) | CCR2 | |
| SCHEMBL4369364 | 0.79 | KDM4E (0.65) | CCR2 | |
| SCHEMBL6959898 | 0.79 | ACLY (0.61) | ACLYCCR2PPARGPPARDPPARA | |
| SCHEMBL6407386 | 0.78 | CCR2 (0.52) | ACLYCCR2RXFP1MEN1KMT2A | |
| SCHEMBL6953098 | 0.78 | CCR2 (0.75) | ACLYCCR2PPARGPPARDPPARA | |
| SCHEMBL3137788 | 0.78 | ACLY (0.63) | ACLYCCR2PPARGPPARDPPARA | |
| SCHEMBL43328 | 0.78 | KDM4E (0.66) | CCR2RXFP1MEN1KMT2A | |
| SCHEMBL1307861 | 0.77 | ACLY (0.41) | ACLYCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | claimed |
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | disclosed |