Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661277 | 0.98 | PLAAT3 (0.51) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL11356452 | 0.96 | TDP1 (0.50) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL4367534 | 0.96 | TDP1 (0.50) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| Water SCHEMBL28390285 | 0.96 | TDP1 (0.50) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL11357520 | 0.96 | TDP1 (0.50) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| Hydrochloric Acid SCHEMBL1421839 | 0.96 | TDP1 (0.50) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| Methyl Alcohol SCHEMBL28046580 | 0.96 | TDP1 (0.50) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| Alcohol SCHEMBL29199086 | 0.92 | TDP1 (0.48) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL660116 | 0.92 | IGF1R (0.52) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL20330088 | 0.90 | NAAA (0.52) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103271083-B | Multi-functional ionic liquid compositions | 阿拉巴马大学 | 2017-08-11 | — | — | CN | disclosed |
| CN-106061940-A | Compounds for treating diabetes and complications resulting therefrom | 本古里安大学内盖夫研究发展局 | 2016-10-26 | — | — | CN | disclosed |
| CN-103271083-A | Multi-functional ionic liquid compositions | UNIV ALABAMA | 2013-09-04 | — | — | CN | disclosed |
| CN-101326275-B | Multifunctional ionic liquid composition | UNIV ALABAMA | 2013-06-05 | — | — | CN | disclosed |
| CN-101137368-B | Roflumilast for the treatment of diabetes | NYCOMED GMBH | 2012-05-16 | — | — | CN | disclosed |
| CN-102225046-A | Transdermal drug delivery formulation | NUVO RES INC | 2011-10-26 | — | — | CN | disclosed |
| CN-101296691-B | Transdermal drug delivery dosage form | NUVO RES INC | 2011-07-27 | — | — | CN | disclosed |
| US-20090289071-A1 | Flow Through Components with an Antimicrobial Lining | THE BOC GROUP, INC. (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090291021-A1 | Methods for Preventing Microbial Colonization of Gas Cylinders and Coupling Components | THE BOC GROUP, INC. (US) | 2009-11-26 | — | — | US | disclosed |
| CN-101326275-A | Multifunctional ionic liquid composition | UNIV ALABAMA (US) | 2008-12-17 | — | — | CN | disclosed |
| US-20080173651-A1 | Antimicrobial Lining for Gas Cylinders and Coupling Components | THE BOC GROUP, INC. | 2008-07-24 | — | — | US | disclosed |
| CN-101137368-A | Roflumilast for the treatment of diabetes | NYCOMED GMBH (DE) | 2008-03-05 | — | — | CN | disclosed |
| EP-1768638-A2 | ANTIMICROBIAL LINING FOR GAS CYLINDERS AND COUPLING COMPONENTS | THE BOC GROUP, INC. (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006088484-A2 | ANTIMICROBIAL LINING FOR GAS CYLINDERS AND COUPLING COMPONENTS | THE BOC GROUP, INC. (US) | 2006-08-24 | — | — | WO | disclosed |
| US-5912120-A | DIAGNOSING PATIENT WITH S-MEPHENYTOIN 4'-HYDROXYLASE DEFICIENCY BY ANALYZING NUCLEIC ACIDS FOR POLYMORPHISMS; AVOIDING PRESCRIBING DRUGS TO PATIENTS WHO CANNOT METABOLIZE THEM | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, (US) | 1999-06-15 | — | — | US | disclosed |
| US-5786191-A | SCREENING A DRUG TEST BY METABOLIZING THE DRUG WITH A CYTOCHROME POLYPEPTIDE | UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 1998-07-28 | — | — | US | disclosed |
| WO-1995030766-A1 | CLONING, EXPRESSION AND DIAGNOSIS OF HUMAN CYTOCHROME P450 2C19: THE PRINCIPAL DETERMINANT OF S-MEPHENYTOIN METABOLISM | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-11-16 | — | — | WO | disclosed |
| US-5047429-A | Treatment of oedema | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4933178-A | Metal-based antimicrobial coating | BIOINTERFACE TECHNOLOGIES, INC. (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0338415-A2 | Use of sulphonylureas in the treatment of oedema | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-25 | — | — | EP | disclosed |