Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380524 | 0.92 | EPHX1 (0.41) | EPHX1APLNRFAAHMEN1KMT2A | |
| SCHEMBL4373581 | 0.92 | EPHX1 (0.41) | EPHX1APLNRFAAHMEN1KMT2A | |
| SCHEMBL4374875 | 0.89 | POLB (0.42) | APLNRFAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL4542690 | 0.86 | EPHX1 (0.39) | EPHX1APLNRFAAHMEN1KMT2A | |
| SCHEMBL4375499 | 0.83 | CNR1 (0.49) | FAAHCNR2 | |
| SCHEMBL4383466 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1RAB9ATNK2 | |
| SCHEMBL4376903 | 0.80 | NPSR1 (0.44) | APLNRFAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL4371244 | 0.80 | NPSR1 (0.44) | APLNRFAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL4368598 | 0.75 | CNR2 (0.42) | CNR2 | |
| SCHEMBL4374742 | 0.75 | TSHR (0.42) | FAAHALDH1A1RAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |