Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4374742 | 0.92 | TSHR (0.42) | CNR2TSHRCNR1 | |
| SCHEMBL4368758 | 0.91 | CNR1 (0.51) | CNR2TSHRCNR1 | |
| SCHEMBL4367945 | 0.90 | CNR1 (0.49) | CNR2TSHRCNR1 | |
| SCHEMBL4370563 | 0.90 | CNR1 (0.49) | CNR2TSHRCNR1 | |
| SCHEMBL4372987 | 0.88 | CNR1 (0.39) | CNR2TSHRCNR1 | |
| SCHEMBL4423581 | 0.86 | CNR1 (0.46) | CNR1 | |
| SCHEMBL4371543 | 0.86 | CNR1 (0.53) | CNR2TSHRCNR1 | |
| SCHEMBL4373433 | 0.86 | ALDH1A1 (0.40) | CNR2TSHR | |
| SCHEMBL4375089 | 0.85 | CNR1 (0.39) | CNR1 | |
| SCHEMBL4376045 | 0.84 | TSHR (0.42) | CNR2TSHRCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |