⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321974 | 0.88 | — | — | |
| SCHEMBL4795425 | 0.85 | — | — | |
| SCHEMBL7519620 | 0.82 | MMP9 (0.35) | — | |
| SCHEMBL13697137 | 0.74 | HCRTR1 (0.32) | — | |
| SCHEMBL4087184 | 0.74 | HCRTR1 (0.32) | — | |
| SCHEMBL14449048 | 0.74 | HCRTR1 (0.32) | — | |
| SCHEMBL756177 | 0.74 | HCRTR1 (0.32) | — | |
| SCHEMBL4795429 | 0.68 | — | — | |
| SCHEMBL7756780 | 0.68 | MMP9 (0.35) | — | |
| SCHEMBL4665617 | 0.68 | MMP9 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281301-A1 | Manufacturing Process of 2' ,2' - Difluoronucleoside and Intermediate | DONG-A-PHARM.CO LTD (KR) | 2009-11-12 | — | — | US | claimed |
| EP-1960378-A1 | A MANUFACTURING PROCESS OF 2',2'-DIFLUORONUCLEOSIDE AND INTERMEDIATE | Dong-A Pharmaceutical Co., Ltd. (KR) | 2008-08-27 | — | — | EP | claimed |
| WO-2007069838-A1 | A MANUFACTURING PROCESS OF 2',2'-DIFLUORONUCLEOSIDE AND INTERMEDIATE | DONG-A PHARM.CO., LTD. (KR) | 2007-06-21 | — | — | WO | claimed |
| EP-0306190-B1 | Process for preparing intermediates useful in the preparation of 2',2'-difluoronucleosides | LILLY CO ELI (US) | 1998-04-08 | — | — | EP | claimed |
| US-20090281301-A1 | Manufacturing Process of 2' ,2' - Difluoronucleoside and Intermediate | DONG-A-PHARM.CO LTD (KR) | 2009-11-12 | — | — | US | disclosed |
| EP-1960378-A1 | A MANUFACTURING PROCESS OF 2',2'-DIFLUORONUCLEOSIDE AND INTERMEDIATE | Dong-A Pharmaceutical Co., Ltd. (KR) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007069838-A1 | A MANUFACTURING PROCESS OF 2',2'-DIFLUORONUCLEOSIDE AND INTERMEDIATE | DONG-A PHARM.CO., LTD. (KR) | 2007-06-21 | — | — | WO | disclosed |