Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21878140 | 0.80 | MMP9 (0.32) | MMP9MMP1MMP2 | |
| SCHEMBL21878137 | 0.80 | MMP9 (0.32) | MMP9MMP1MMP2 | |
| SCHEMBL21878139 | 0.80 | MMP9 (0.32) | MMP9MMP1MMP2 | |
| SCHEMBL7519620 | 0.77 | MMP9 (0.35) | MMP9MMP1MMP2 | |
| SCHEMBL6581604 | 0.73 | MMP9 (0.32) | MMP9MMP1MMP2 | |
| SCHEMBL6765429 | 0.73 | MMP9 (0.34) | MMP9MMP1MMP2 | |
| SCHEMBL2757777 | 0.73 | MMP9 (0.32) | MMP9MMP1MMP2 | |
| SCHEMBL2871627 | 0.72 | MMP9 (0.32) | MMP9MMP1MMP2 | |
| SCHEMBL13381148 | 0.68 | MMP9 (0.31) | MMP9MMP1MMP2 | |
| SCHEMBL4375722 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602262-A | Process for the preparation of 2-deoxy-2,2-difluoro-β-D-ribo-pentopyranose | ELI LILLY AND COMPANY (US) | 1997-02-11 | — | — | US | claimed |
| EP-0727432-A1 | Process for the preparation of 2-deoxy-2,2-difluoro-beta-d-ribo-pentopyranose | ELI LILLY AND COMPANY (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0727433-B1 | Process for the preparation of 1-(2'-deoxy-2',2'-difluoro-d-ribo-pentofuranosyl)-cytosine from 2-deoxy-2,2-difluoro-beta-d-ribo-pentopyranose | LILLY CO ELI (US) | 2001-03-14 | — | — | EP | disclosed |
| US-5602262-A | Process for the preparation of 2-deoxy-2,2-difluoro-β-D-ribo-pentopyranose | ELI LILLY AND COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| US-5559222-A | Preparation of 1-(2'-deoxy-2',2'-difluoro-D-ribo-pentofuranosyl)-cytosine from 2-deoxy-2,2-difluoro-β-D-ribo-pentopyranose | ELI LILLY AND COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0727433-A1 | Process for the preparation of 1-(2'-deoxy-2',2'-difluoro-d-ribo-pentofuranosyl)-cytosine from 2-deoxy-2,2-difluoro-beta-d-ribo-pentopyranose | ELI LILLY AND COMPANY (US) | 1996-08-21 | — | — | EP | disclosed |
| EP-0727432-A1 | Process for the preparation of 2-deoxy-2,2-difluoro-beta-d-ribo-pentopyranose | ELI LILLY AND COMPANY (US) | 1996-08-21 | — | — | EP | disclosed |
| EP-0727432-A1 | Process for the preparation of 2-deoxy-2,2-difluoro-beta-d-ribo-pentopyranose | ELI LILLY AND COMPANY (US) | 1996-08-21 | — | — | EP | disclosed |