SCHEMBL4375792

SCHEMBL4375792

CCN1C(=O)c2cccc([N+](=O)[O-])c2C1=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA9 Q16790 2/20 0.59
CA12 O43570 1/20 0.59
TDP1 Q9NUW8 1/20 0.58
CA4 P22748 1/20 0.56
ATM Q13315 1/20 0.55
LMNA P02545 1/20 0.55
S100A4 P26447 2/20 0.53
ACHE P22303 1/20 0.50
CYP1B1 Q16678 1/20 0.50
KDM4E B2RXH2 1/20 0.49
PTPRC P08575 1/20 0.49
ALDH1A1 P00352 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
MAPT P10636 1/20 0.47
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30050782 1.00 CA1 (0.59) CA1CA2CA9CA12TDP1
SCHEMBL9394327 0.91 S100A4 (0.58) CA1CA2CA9CA12TDP1
SCHEMBL9397083 0.91 S100A4 (0.54) CA1CA2CA9CA12TDP1
SCHEMBL8091427 0.88 CA1 (0.60) CA1CA2CA9CA12TDP1
SCHEMBL8090181 0.85 CA1 (0.58) CA1CA2CA9CA12TDP1
SCHEMBL11314968 0.84 CA1 (0.63) CA1CA2CA9CA12TDP1
SCHEMBL6961551 0.84 CA1 (0.59) CA1CA2CA9CA12TDP1
SCHEMBL29217854 0.84 CA1 (0.55) CA1CA2CA9CA12TDP1
SCHEMBL8090169 0.83 POLB (0.58) CA1CA2CA9CA12TDP1
SCHEMBL11307275 0.83 POLB (0.64) CA1CA2CA9CA12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504556-A Bisphenol phthaloyl Process for producing imine 潍坊弘润石化科技有限公司 2025-02-25 CN claimed
CN-119504556-A Bisphenol phthaloyl Process for producing imine 潍坊弘润石化科技有限公司 2025-02-25 CN disclosed
CN-114349678-B Continuous industrial production method of N-alkyl-nitrophthalimide 珠海派锐尔新材料有限公司 2024-04-26 CN disclosed
CN-116903517-A Preparation method of 4-nitro-N-alkylphthalimide 广东优巨先进新材料股份有限公司 2023-10-20 CN disclosed
CN-114349678-A Continuous industrial production method of N-alkyl-nitrophthalimide 珠海派锐尔新材料有限公司 2022-04-15 CN disclosed
US-20110263540-A1 SMALL-MOLECULE INHIBITORS OF PROTEIN SYNTHESIS INACTIVATING TOXINS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2011-10-27 US disclosed
US-20100010060-A1 Isoindolin-1-One-, Isoindolin-3-One- and Isoindolin-1,3-Dione-Derivatives and Use Thereof BAYER HEALTHCARE AG (DE) 2010-01-14 US disclosed
WO-2009118596-A2 PHTHALIMIDE DERIVATIVES AS TRPA1 MODULATORS GLENMARK PHARMACEUTICALS, S. A. (CH) 2009-10-01 WO disclosed
US-7244847-B2 Benzimidazole compounds ISIS PHARMACEUTICALS, INC. (US) 2007-07-17 US disclosed
US-4506083-A INITIATORS FOR PHOTOPOLYMERIZATION OR PHOTOCHEMICAL CROSSLINKING CIBA-GEIGY CORPORATION (US) 1985-03-19 US disclosed
US-4505794-A PHOTOINITIATORS WITH AMINES FOR PHOTOPOLYMERIZATION OF UNSATURATEDCOMPOUNDS; SOLUBILITY CIBA-GEIGY CORPORATION (US) 1985-03-19 US disclosed
US-4324719-A YELLOW TO BLUE SHADES ON NYLON CARPET EASTMAN KODAK COMPANY (US) 1982-04-13 US disclosed
US-4039522-A Phthalimidyl-azo-m-acylamido-n-substituted aniline compounds and polyester fibers dyed therewith EASTMAN KODAK COMPANY (US) 1977-08-02 US disclosed
US-4012372-A MONOAZO DISPERSE DYES EASTMAN KODAK COMPANY (US) 1977-03-15 US disclosed
US-3980634-A Phthalimidyl-azo aniline type compounds and polyester fibers dyed therewith EASTMAN KODAK COMPANY (US) 1976-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263540-A1 SMALL-MOLECULE INHIBITORS OF PROTEIN SYNTHESIS INACTIVATING TOXINS MRPS27, MRPS22, MRPS23 CA1 3560/4885CA2 3955/4885CA9 4617/4885
US-20100010060-A1 Isoindolin-1-One-, Isoindolin-3-One- and Isoindolin-1,3-Dione-Derivatives and Use Thereof ICAM1, SERPINC1, TFPI2 CA1 4613/4885CA2 4238/4885CA9 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.