⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269414 | 0.77 | TRPA1 (0.32) | — | |
| SCHEMBL270974 | 0.74 | — | — | |
| SCHEMBL270291 | 0.72 | — | — | |
| SCHEMBL4444170 | 0.71 | — | — | |
| SCHEMBL4187400 | 0.69 | — | — | |
| SCHEMBL270333 | 0.68 | — | — | |
| SCHEMBL276718 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL13624144 | 0.65 | — | — | |
| SCHEMBL4147977 | 0.65 | — | — | |
| SCHEMBL6902075 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487171-A1 | Dihydrobenzopyran, thiochroman, tetrahydroquinoleine and tetrahydronaphthalene derivatives and their use in anti-cancer therapy | Université de Liège (BE) | 2012-08-15 | — | — | EP | disclosed |
| EP-1432684-B1 | PYRIDINIC SULFONAMIDE DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | UNIV LIEGE (BE) | 2009-03-25 | — | — | EP | disclosed |
| US-20070173534-A1 | Pyridinic sulfonamide derivatives method of production and use thereof | UNIVERSITE DE LIEGE | 2007-07-26 | — | — | US | disclosed |
| US-7226936-B2 | Pyridinic sulfonamide derivatives method of production and use thereof | UNIVERSITY DE LIEGE (BE) | 2007-06-05 | — | — | US | disclosed |
| EP-1716120-A1 | HERBICIDAL HETEROAROYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005061464-A1 | HERBICIDAL HETEROAROYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-07 | — | — | WO | disclosed |
| US-20050020642-A1 | Pyridinic sulfonamide derivatives method of production and use thereof | UNIVERSITE DE LIEGE (BE) | 2005-01-27 | — | — | US | disclosed |
| EP-1144401-A3 | THIOCHROMANOYL CYCLOHEXENONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | disclosed |
| EP-1181295-A2 | TRICYCLIC BENZOYLCYCLOHEXANEDIONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| EP-1163240-A1 | TRICYCLIC BENZOYLPYRAZOLE DERIVATIVES USED AS A HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-19 | — | — | EP | disclosed |
| WO-1999057111-A9 | CYCLOHEXENONDIOXOTHIO CHROMANOYL DERIVATIVES | BASF AG (DE) | 2001-03-01 | — | — | WO | disclosed |
| WO-2000073311-A2 | TRICYCLIC BENZOYLCYCLOHEXANEDIONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000059910-A2 | TRICYCLIC PYRAZOLONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-12 | — | — | WO | disclosed |
| WO-2000059911-A2 | TRICYCLIC CYCLOHEXANEDIONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-12 | — | — | WO | disclosed |
| WO-2000055158-A1 | TRICYCLIC BENZOYLPYRAZOLE DERIVATIVES USED AS A HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-21 | — | — | WO | disclosed |
| WO-2000035903-A2 | THIOCHROMANOYL CYCLOHEXENONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-22 | — | — | WO | disclosed |
| WO-2000034270-A1 | THIOCHROMANOYLPYRAZOLONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000014069-A1 | CYCLOHEXENONQUINOLINOYL-DERIVATIVES AS HERBICIDAL AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-16 | — | — | WO | disclosed |
| WO-1999059991-A1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
| WO-1999057111-A1 | CYCLOHEXENONDIOXOTHIO CHROMANOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-11 | — | — | WO | disclosed |