Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.86 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.86 |
| ▸ | ACHE | P22303 | 4/20 | 0.86 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.86 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.86 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.86 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CA12 | O43570 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Psoralen SCHEMBL29503678 | 0.93 | MAOA (1.00) | MAOAKDM4EHSD17B10CYP3A4ACHE | |
| Psoralen SCHEMBL17835 | 0.93 | MAOA (1.00) | MAOAKDM4EHSD17B10CYP3A4ACHE | |
| Psoralen SCHEMBL2684633 | 0.93 | MAOA (1.00) | MAOAKDM4EHSD17B10CYP3A4ACHE | |
| Psoralen SCHEMBL29165499 | 0.91 | MAOA (0.96) | MAOAKDM4EHSD17B10CYP3A4ACHE | |
| Psoralen SCHEMBL8707426 | 0.91 | MAOA (0.96) | MAOAKDM4EHSD17B10CYP3A4ACHE | |
| Psoralen SCHEMBL28036058 | 0.91 | MAOA (0.96) | MAOAKDM4EHSD17B10CYP3A4ACHE | |
| Psoralen SCHEMBL3647286 | 0.91 | MAOA (0.96) | MAOAKDM4EHSD17B10CYP3A4ACHE | |
| Psoralen SCHEMBL27405230 | 0.91 | MAOA (0.96) | MAOAKDM4EHSD17B10CYP3A4ACHE | |
| Psoralen SCHEMBL28497870 | 0.90 | KDM4E (0.86) | MAOAKDM4EHSD17B10CYP3A4ACHE | |
| SCHEMBL11458294 | 0.87 | HSD17B10 (0.89) | MAOAKDM4EHSD17B10CYP3A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071642-B2 | Dimethyl amino ethyl ether psoralens and methods for their production and use | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090155224-A1 | Dimethyl amino ethyl ether psoralens and methods for their production and use | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155224-A1 | Dimethyl amino ethyl ether psoralens and methods for their production and use | HLA-C, HLA-A, HLA-B | MAOA 2979/4885KDM4E 175/4885HSD17B10 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.