SCHEMBL11458294

SCHEMBL11458294

O=c1ccc2cc3occc3cc2o1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.89
KDM4E B2RXH2 4/20 0.89
CYP3A4 P08684 4/20 0.89
MAOA P21397 3/20 0.89
ACHE P22303 3/20 0.89
NFKB1 P19838 2/20 0.89
CYP2A6 P11509 2/20 0.89
CYP2D6 P10635 2/20 0.89
CYP2C19 P33261 2/20 0.89
CYP2C9 P11712 1/20 0.89
CA12 O43570 7/20 0.57
CA9 Q16790 7/20 0.57
MCL1 Q07820 6/20 0.57
ALDH1A1 P00352 6/20 0.57
HPGD P15428 5/20 0.57
AKR1B1 P15121 4/20 0.57
GAA P10253 3/20 0.57
MAPT P10636 3/20 0.57
LMNA P02545 3/20 0.57
GLA P06280 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Psoralen SCHEMBL17835 0.94 MAOA (1.00) HSD17B10KDM4ECYP3A4MAOAACHE
Psoralen SCHEMBL29503678 0.94 MAOA (1.00) HSD17B10KDM4ECYP3A4MAOAACHE
Psoralen SCHEMBL2684633 0.94 MAOA (1.00) HSD17B10KDM4ECYP3A4MAOAACHE
Psoralen SCHEMBL8707426 0.92 MAOA (0.96) HSD17B10KDM4ECYP3A4MAOAACHE
Psoralen SCHEMBL27405230 0.92 MAOA (0.96) HSD17B10KDM4ECYP3A4MAOAACHE
Psoralen SCHEMBL3647286 0.92 MAOA (0.96) HSD17B10KDM4ECYP3A4MAOAACHE
Psoralen SCHEMBL29165499 0.92 MAOA (0.96) HSD17B10KDM4ECYP3A4MAOAACHE
Psoralen SCHEMBL28036058 0.92 MAOA (0.96) HSD17B10KDM4ECYP3A4MAOAACHE
Psoralen SCHEMBL4376218 0.87 MAOA (0.86) HSD17B10KDM4ECYP3A4MAOAACHE
Psoralen SCHEMBL28497870 0.87 KDM4E (0.86) HSD17B10KDM4ECYP3A4MAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4230624-A CYCLIZATION, BASIC CATALYSTS AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (FR) 1980-10-28 US disclosed