Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126833 | 0.79 | TSHR (0.40) | TSHR | |
| SCHEMBL10001939 | 0.76 | ALDH1A1 (0.36) | SIGMAR1CYP1A2CYP2D6TSHR | |
| SCHEMBL28678933 | 0.75 | TSHR (0.36) | SIGMAR1TSHR | |
| SCHEMBL15198674 | 0.74 | — | — | |
| SCHEMBL2809739 | 0.72 | TDP1 (0.43) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9152846 | 0.71 | TDP1 (0.45) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL110199 | 0.70 | TDP1 (0.48) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14847559 | 0.70 | ACE2 (0.37) | SIGMAR1TSHR | |
| SCHEMBL15362279 | 0.70 | TSHR (0.32) | TSHR | |
| SCHEMBL13800448 | 0.69 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065384-A1 | FLUORESCENT MRI PROBE | THE UNIVERSITY OF TOKYO (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065384-A1 | FLUORESCENT MRI PROBE | GLRA1, GLRA3, GDI1 | SIGMAR1 1632/4885TP53 972/4885CYP1A2 4201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.