Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cinoxacin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinoxacin SCHEMBL43770 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1LMNATSHRBLM | |
| Cinoxacin SCHEMBL28034322 | 0.99 | KDM4E (0.97) | KDM4EALDH1A1LMNATSHRBLM | |
| Cinoxacin SCHEMBL28034323 | 0.99 | KDM4E (0.97) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11154799 | 0.90 | ALDH1A1 (0.82) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11153077 | 0.90 | ALDH1A1 (0.81) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL16450335 | 0.90 | ALDH1A1 (0.81) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11148183 | 0.88 | ALDH1A1 (0.78) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11669307 | 0.86 | ALDH1A1 (0.76) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11149177 | 0.86 | ALDH1A1 (0.75) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11035052 | 0.84 | ALDH1A1 (0.72) | KDM4EALDH1A1LMNATSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021402-B1 | THIXOTROPIC DELIVERY SYSTEMS | UNIV OF MONTANA (US) | 2025-08-20 | — | — | EP | claimed |
| CN-111461805-B | Method and system for controlling second killing based on nginx and electronic equipment | 北京京东尚科信息技术有限公司 | 2025-05-23 | — | — | CN | claimed |
| EP-4539987-A1 | PROCESS FOR PREPARATION OF 2-D NANOSTRUCTURED SHEET BASED PHOTOCATALYST AND APPLICATION THEREOF | Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) | 2025-04-23 | — | — | EP | claimed |
| CN-117938628-A | Remote monitoring service downtime method | 浪潮通信信息系统(天津)有限公司 | 2024-04-26 | — | — | CN | claimed |
| WO-2023242864-A1 | PROCESS FOR PREPARATION OF 2-D NANOSTRUCTURED SHEET BASED PHOTOCATALYST AND APPLICATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-12-21 | — | — | WO | claimed |
| EP-2916820-B1 | DELIVERY OF BIOLOGICALLY-ACTIVE AGENTS USING VOLATILE, HYDROPHOBIC SOLVENTS | ROCHAL TECH LLC (US) | 2023-10-11 | — | — | EP | claimed |
| CN-116501335-B | Deployment method, device and medium of one-stop type station building system | 北京安锐卓越信息技术股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116501335-A | Deployment method, device and medium of one-stop type station building system | 北京安锐卓越信息技术股份有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-116187239-A | Improved BRPUF circuit and FPGA IP core system based on improved BRPUF circuit | 无锡元信芯云科技有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-114782998-A | Abnormal behavior recognition method, system, device and medium with enhanced skeleton joint points | 上海大学 | 2022-07-22 | — | — | CN | claimed |
| CN-113729735-B | Emotional electroencephalogram feature representation method based on multi-domain self-adaptive graph convolution neural network | 上海交通大学 | 2022-05-17 | — | — | CN | claimed |
| EP-3067047-B1 | LIPID-BASED COMPOSITIONS OF ANTIINFECTIVES FOR TREATING PULMONARY INFECTIONS | INSMED INC (US) | 2022-04-20 | — | — | EP | claimed |
| US-20260111307-A1 | ERROR CORRECTION CODE ENGINE OF SEMICONDUCTOR MEMORY DEVICE AND SEMICONDUCTOR MEMORY DEVICE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2026-04-23 | — | — | US | disclosed |
| US-12568374-B2 | Cloud computing environment and a method for providing remote secure element services | SAFEPAY SYSTEMS KFT (HU) | 2026-03-03 | — | — | US | disclosed |
| US-12554576-B2 | Error correction code engine of semiconductor memory device and semiconductor memory device | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2026-02-17 | — | — | US | disclosed |
| US-20260033494-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | TEXAS A & M UNIV SYS (US) | 2026-02-05 | — | — | US | disclosed |
| CN-113729735-B | Emotional electroencephalogram feature representation method based on multi-domain self-adaptive graph convolution neural network | 上海交通大学 | 2022-05-17 | — | — | CN | disclosed |
| US-11318141-B2 | Methods and compositions related to STK1-targeted small molecules as antibiotic resistance breakers | OHIO STATE INNOVATION FOUNDATION (US) | 2022-05-03 | — | — | US | disclosed |
| CN-114392748-A | Application of monolithic catalyst in catalytic decomposition of ozone | 中国科学院生态环境研究中心 | 2022-04-26 | — | — | CN | disclosed |
| US-20220101841-A1 | SPEECH RECOGNITION | CIRRUS LOGIC INTERNATIONAL SEMICONDUCTOR LTD. (GB) | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12554576-B2 | Error correction code engine of semiconductor memory device and semiconductor memory device | DNMT3A, BRCA1, EPHA6 | KDM4E 1820/4885ALDH1A1 4192/4885LMNA 4152/4885 |
| US-20260033494-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | MYB, DDT, PDE1C | KDM4E 1819/4885ALDH1A1 4194/4885LMNA 3130/4885 |
| US-20260111307-A1 | ERROR CORRECTION CODE ENGINE OF SEMICONDUCTOR MEMORY DEVICE AND SEMICONDUCTOR MEMORY DEVICE | BRCA1, DNMT3A, ALPP | KDM4E 2070/4885ALDH1A1 4266/4885LMNA 3834/4885 |
| US-11318141-B2 | Methods and compositions related to STK1-targeted small molecules as antibiotic resistance breakers | STK3, STK4, STK35 | KDM4E 1014/4885ALDH1A1 3579/4885LMNA 1544/4885 |
| US-12568374-B2 | Cloud computing environment and a method for providing remote secure element services | CTCF, STUB1, CXCR2 | KDM4E 1230/4885ALDH1A1 3824/4885LMNA 4439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.