Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382793 | 0.96 | KMT2A (0.35) | HDAC1HDAC6HDAC3HDAC2HDAC10 | |
| SCHEMBL1603410 | 0.88 | HDAC3 (0.31) | HDAC1HDAC6HDAC3HDAC2HDAC10 | |
| SCHEMBL4385124 | 0.86 | HDAC1 (0.38) | HDAC1HDAC6HDAC3HDAC2HDAC10 | |
| SCHEMBL1603303 | 0.84 | DRD2 (0.31) | DRD2 | |
| SCHEMBL4370788 | 0.83 | HDAC3 (0.33) | HDAC1HDAC6HDAC3HDAC2HDAC10 | |
| SCHEMBL1603218 | 0.79 | HDAC3 (0.32) | HDAC1HDAC6HDAC3HDAC2HDAC10 | |
| SCHEMBL1602668 | 0.75 | DRD2 (0.31) | DRD2 | |
| SCHEMBL4377347 | 0.70 | — | — | |
| SCHEMBL4382791 | 0.68 | ELANE (0.31) | — | |
| SCHEMBL16847503 | 0.68 | SMN1; SMN2 (0.50) | LMNAHTTALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658503-B1 | CHEMILUMINESCENT COMPOUNDS | MOLECULAR LIGHT TECH RES LTD (GB) | 2009-11-18 | — | — | EP | claimed |