Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4377350 | 0.96 | HDAC1 (0.36) | KMT2AMEN1ALDH1A1HSD17B10GAA | |
| SCHEMBL1603303 | 0.88 | DRD2 (0.31) | DRD3DRD2 | |
| SCHEMBL4370788 | 0.86 | HDAC3 (0.33) | KMT2AMEN1ALDH1A1HSD17B10GAA | |
| SCHEMBL1603410 | 0.85 | HDAC3 (0.31) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4385124 | 0.83 | HDAC1 (0.38) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1602668 | 0.78 | DRD2 (0.31) | DRD3DRD2 | |
| SCHEMBL1603218 | 0.75 | HDAC3 (0.32) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12892565 | 0.70 | MEN1 (0.51) | KMT2AMEN1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL4382791 | 0.69 | ELANE (0.31) | — | |
| SCHEMBL4532049 | 0.69 | HDAC4 (0.37) | KMT2AALDH1A1HPGDHDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658503-B1 | CHEMILUMINESCENT COMPOUNDS | MOLECULAR LIGHT TECH RES LTD (GB) | 2009-11-18 | — | — | EP | claimed |