Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4378868 | 0.98 | ADRB2 (0.48) | ADRB2ALDH1A1L3MBTL1KDM4EADRB1 | |
| SCHEMBL3273405 | 0.89 | ADRB2 (0.48) | ADRB2ALDH1A1L3MBTL1KDM4EADRB1 | |
| SCHEMBL19352867 | 0.85 | SMN1; SMN2 (0.50) | ADRB2ALDH1A1L3MBTL1KDM4EADRB1 | |
| SCHEMBL11742820 | 0.84 | AOC3 (0.46) | ADRB2ALDH1A1L3MBTL1KDM4EADRB1 | |
| SCHEMBL5848458 | 0.81 | AOC3 (0.46) | ADRB2ALDH1A1L3MBTL1KDM4EADRB1 | |
| SCHEMBL2292474 | 0.77 | HIF1A (0.53) | ADRB2ALDH1A1L3MBTL1KDM4EAOC3 | |
| SCHEMBL2294187 | 0.77 | HIF1A (0.53) | ADRB2ALDH1A1L3MBTL1KDM4EAOC3 | |
| SCHEMBL1991793 | 0.76 | NPC1 (0.57) | ADRB2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL1991791 | 0.76 | NPC1 (0.57) | ADRB2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL7298571 | 0.76 | KDM4E (0.63) | ADRB2ALDH1A1L3MBTL1KDM4EADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119709-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERAZINE DERIVATIVE | Kaneka Corporation (JP) | 2009-11-18 | — | — | EP | disclosed |