Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.47 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442328 | 0.93 | NR4A2 (0.47) | NR4A2SOS2NCF1EHMT2EHMT1 | |
| SCHEMBL16604815 | 0.79 | TLR8 (0.39) | NR4A2SOS2MEN1KMT2AKDM4E | |
| SCHEMBL18670877 | 0.79 | TLR8 (0.41) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL21591888 | 0.77 | EGFR (0.50) | EGFRSRC | |
| SCHEMBL21591890 | 0.76 | SMN1; SMN2 (0.44) | NR4A2SOS2NCF1MEN1KMT2A | |
| SCHEMBL29362546 | 0.76 | SMN1; SMN2 (0.44) | NR4A2SOS2NCF1MEN1KMT2A | |
| SCHEMBL24532356 | 0.73 | LMNA (0.52) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL29681624 | 0.73 | LMNA (0.52) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL3302189 | 0.72 | ALDH1A1 (0.35) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL31285386 | 0.72 | NR4A2 (0.61) | NR4A2SOS2NCF1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |