Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10075679 | 0.78 | AR (0.48) | AR | |
| SCHEMBL1720400 | 0.78 | AR (0.48) | AR | |
| SCHEMBL7136117 | 0.64 | AR (0.55) | AR | |
| SCHEMBL5943005 | 0.64 | TLR9 (0.46) | AR | |
| SCHEMBL7074512 | 0.62 | AR (0.35) | AR | |
| SCHEMBL10069183 | 0.62 | AR (0.43) | AR | |
| SCHEMBL7178500 | 0.62 | AR (0.47) | AR | |
| SCHEMBL30366895 | 0.62 | AR (0.46) | AR | |
| SCHEMBL6484968 | 0.60 | ALDH1A1 (0.52) | AR | |
| SCHEMBL31131411 | 0.60 | LRRK2 (0.37) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626036-B2 | 4-(3a-Methyl-1,3-dioxo-5-trifluoromethyl-3a,4-dihydro-3H-1l4-thia-2,6,6a-triaza-pentalen-2-yl)-2-trifluoromethyl-benzonitrile; anticarcinogenic agents; prostate glands; benign prostatic hyperplasia; alopecia; eating disorders; mammary glands; acne; AIDS; cachexia; male contraceptives; sexual disorders | JANSSEN PHARMACEUTICA NV (BE) | 2009-12-01 | — | — | US | claimed |