Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074512 | 0.82 | AR (0.35) | ARNOTUMHTR1AADRA1AADRA1B | |
| SCHEMBL31131411 | 0.80 | LRRK2 (0.37) | ARNOTUMPRKCAPRKCQGRM2 | |
| SCHEMBL31131403 | 0.75 | ALDH1A1 (0.46) | AR | |
| SCHEMBL3602754 | 0.71 | AR (1.00) | AR | |
| SCHEMBL2784093 | 0.70 | ALDH1A1 (0.46) | HTR1A | |
| SCHEMBL6484968 | 0.69 | ALDH1A1 (0.52) | ARNOTUMPDK2PGR | |
| SCHEMBL25983090 | 0.69 | AR (0.46) | ARPDK2PGR | |
| SCHEMBL7178500 | 0.69 | AR (0.47) | AR | |
| SCHEMBL8368695 | 0.68 | DRD2 (0.39) | ARHTR1A | |
| SCHEMBL2947316 | 0.68 | LMNA (0.49) | HTR1AADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144366-A3 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC. (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-1144366-A2 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000037430-A2 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC. (US) | 2000-06-29 | — | — | WO | disclosed |