Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | TSPO | P30536 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240141 | 0.98 | CYP1A2 (0.52) | KDM4ECYP1A2CYP2C19FABP4FABP5 | |
| SCHEMBL4381323 | 0.98 | CYP1A2 (0.52) | KDM4ECYP1A2CYP2C19FABP4FABP5 | |
| SCHEMBL13825878 | 0.89 | ALDH1A1 (0.56) | KDM4ECYP1A2CYP2C19FABP4FABP5 | |
| SCHEMBL25193015 | 0.78 | FABP4 (0.55) | KDM4ECYP1A2CYP2C19FABP4FABP5 | |
| SCHEMBL13212785 | 0.78 | CYP1A2 (0.52) | KDM4ECYP1A2CYP2C19FABP4FABP5 | |
| SCHEMBL13825812 | 0.78 | APEX1 (0.52) | KDM4EAGERALDH1A1 | |
| SCHEMBL3010885 | 0.76 | CYP1A2 (0.50) | KDM4ECYP1A2CYP2C19FABP4FABP5 | |
| SCHEMBL31742340 | 0.76 | FABP4 (0.57) | KDM4ECYP1A2CYP2C19FABP4FABP5 | |
| SCHEMBL31233890 | 0.76 | FABP4 (0.57) | KDM4ECYP1A2CYP2C19FABP4FABP5 | |
| SCHEMBL3218835 | 0.76 | FABP4 (0.57) | KDM4ECYP1A2CYP2C19FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629379-B2 | Substituted phosphonate fluorescent sensors and use thereof | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2009-12-08 | — | — | US | disclosed |
| US-20070049761-A1 | Substituted phosphonate fluorescent sensors and use thereof | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049761-A1 | Substituted phosphonate fluorescent sensors and use thereof | NR2E3, CASR, NR3C2 | KDM4E 4496/4885CYP1A2 3952/4885CYP2C19 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.