SCHEMBL437885

SCHEMBL437885

C=CCC(O)(OP(=O)(O)O)C(C)=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 1/20 0.33
LPAR2 Q9HBW0 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9574510 0.87 SMPD1 (0.49) SMPD1LPAR3
SCHEMBL17923947 0.72 LPAR2 (0.34) SMPD1LPAR2LPAR3
Phosphoric Acid SCHEMBL437888 0.72 ALDH1A1 (0.31)
SCHEMBL29053654 0.71 LPAR2 (0.36) SMPD1LPAR2LPAR3
SCHEMBL10716996 0.71 LPAR2 (0.33) SMPD1LPAR2LPAR3
SCHEMBL3360558 0.69 LPAR2 (0.32) SMPD1LPAR2LPAR3
SCHEMBL11316152 0.69 LPAR2 (0.32) SMPD1LPAR2LPAR3
SCHEMBL17923951 0.69 LPAR3 (0.36) SMPD1LPAR2LPAR3
SCHEMBL21596998 0.69 LPAR3 (0.36) SMPD1LPAR2LPAR3
SCHEMBL6271549 0.69 SMPD1 (0.61) SMPD1LPAR2LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014167074-A1 METHODS FOR MODULATING RNA ALTERNATIVE SPLICING IN A SUBJECT IN NEED THEREOF INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2014-10-16 WO disclosed
US-8101818-B2 Expression vector comprising nucleotide sequences coding diacylglycerol acyltransferase for use in generation of transgenic crops with enhanced ricinoleic acid biosynthesis WASHINGTON STATE UNIVERSITY (US) 2012-01-24 US disclosed
US-20080282427-A1 Enhancement of Hydroxy Fatty Acid Accumulation in Oilseed Plants WASHINGTON STATE UNIVERSITY (US) 2008-11-13 US disclosed
EP-1906725-A2 ENHANCEMENT OF HYDROXY FATTY ACID ACCUMULATION IN OILSEED PLANTS Washington State University (US) 2008-04-09 EP disclosed
WO-2006127655-A2 ENHANCEMENT OF HYDROXY FATTY ACID ACCUMULATION IN OILSEED PLANTS WASHINGTON STATE UNIVERSITY (US) 2006-11-30 WO disclosed