SCHEMBL4379158

SCHEMBL4379158

CCOC(C)OC(=O)CC1CC2C=CC1C2

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.36
ALDH1A1 P00352 4/20 0.36
POLB P06746 1/20 0.32
ALOX15 P16050 1/20 0.32
EPHX2 P34913 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
MAPK1 P28482 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4386216 0.87 KDM4E (0.34) KDM4EALDH1A1POLBALOX15EPHX2
SCHEMBL4377524 0.84 KDM4E (0.41) KDM4EALDH1A1POLBALOX15EPHX2
SCHEMBL1089531 0.79 KDM4E (0.41) KDM4EALDH1A1POLBALOX15EPHX2
SCHEMBL3368345 0.77 ALDH1A1 (0.49) KDM4EALDH1A1POLBTDP1MAPT
SCHEMBL5356106 0.76 KDM4E (0.41) KDM4EALDH1A1LMNA
SCHEMBL1087617 0.76 EPHX2 (0.41) KDM4EALDH1A1POLBALOX15EPHX2
SCHEMBL4379431 0.75 KDM4E (0.38) KDM4EALDH1A1POLBALOX15EPHX2
SCHEMBL4739740 0.74 KDM4E (0.40) KDM4EALDH1A1POLBALOX15EPHX2
SCHEMBL13346471 0.73 KDM4E (0.41) KDM4EALDH1A1POLBALOX15EPHX2
SCHEMBL4386382 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211984-B2 Ring-opening metathesis polymer, hydrogenated product thereof, method for preparing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2012-07-03 US disclosed
US-20090215974-A1 RING-OPENING METATHESIS POLYMER, HYDROGENATED PRODUCT THEREOF, METHOD FOR PREPARING THE SAME, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2009-08-27 US disclosed
EP-2045280-A1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2009-04-08 EP disclosed