Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379703 | 1.00 | LMNA (0.49) | LMNAKMT2AMEN1MAOAMAOB | |
| SCHEMBL3482805 | 0.89 | HCAR2 (0.56) | LMNAKMT2AMEN1ALDH1A1HCAR2 | |
| SCHEMBL3482702 | 0.89 | HCAR2 (0.56) | LMNAKMT2AMEN1ALDH1A1HCAR2 | |
| SCHEMBL22423030 | 0.85 | LMNA (0.50) | LMNAKMT2AMEN1MAOBTDP1 | |
| SCHEMBL13474827 | 0.85 | TDP1 (0.60) | LMNAKMT2AMEN1TDP1AKR1B10 | |
| SCHEMBL3482700 | 0.84 | HCAR2 (0.64) | LMNAALDH1A1HCAR2MAPTRAB9A | |
| SCHEMBL3482642 | 0.84 | HCAR2 (0.64) | LMNAALDH1A1HCAR2MAPTRAB9A | |
| SCHEMBL27216283 | 0.84 | HCAR2 (0.64) | LMNAALDH1A1HCAR2MAPTRAB9A | |
| SCHEMBL20888282 | 0.84 | LMNA (0.55) | LMNAKMT2AMEN1MAOBAKR1B10 | |
| SCHEMBL20888034 | 0.84 | LMNA (0.55) | LMNAKMT2AMEN1MAOBAKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744792-B1 | RESORBABLE POLYMERIC MEDICAL GOODS WITH IMPROVED MECHANICAL PROPERTIES AND METHOD FOR PRODUCING SAME | SYNTHES GMBH (CH) | 2018-11-28 | — | — | EP | claimed |
| US-8211351-B2 | Resorbable polymeric medical goods with improved mechanical properties and method for producing same | SYNTHES USA, LLC (US) | 2012-07-03 | — | — | US | claimed |
| US-20090030415-A1 | RESORBABLE POLYMERIC MEDICAL GOODS WITH IMPROVED MECHANICAL PROPERTIES AND METHOD FOR PRODUCING SAME | SYNTHES USA, LLC | 2009-01-29 | — | — | US | claimed |
| EP-1744792-A1 | RESORBABLE POLYMERIC MEDICAL GOODS WITH IMPROVED MECHANICAL PROPERTIES AND METHOD FOR PRODUCING SAME | Synthes GmbH (CH) | 2007-01-24 | — | — | EP | claimed |
| WO-2005110506-A1 | RESORBABLE POLYMERIC MEDICAL GOODS WITH IMPROVED MECHANICAL PROPERTIES AND METHOD FOR PRODUCING SAME | SYNTHES GMBH (CH) | 2005-11-24 | — | — | WO | claimed |