Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CPB1 | P15086 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3203924 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAACPB1NPSR1TAAR1 | |
| SCHEMBL19437142 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAACPB1NPSR1TAAR1 | |
| SCHEMBL4386420 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAACPB1NPSR1TAAR1 | |
| SCHEMBL3223441 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAACPB1NPSR1TAAR1 | |
| SCHEMBL3204209 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAACPB1NPSR1TAAR1 | |
| SCHEMBL3219056 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAACPB1NPSR1TAAR1 | |
| SCHEMBL30221997 | 0.90 | ALDH1A1 (0.56) | ALDH1A1GAACPB1TSHRSMN1; SMN2 | |
| SCHEMBL13643316 | 0.90 | CPB1 (0.50) | ALDH1A1GAACPB1TSHRCA1 | |
| SCHEMBL29553101 | 0.90 | TSHR (0.55) | ALDH1A1GAACPB1TSHRCA1 | |
| SCHEMBL9937871 | 0.90 | ALDH1A1 (0.56) | ALDH1A1GAACPB1TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129224-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | Anadys Pharmaceuticals, Inc. (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008124450-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |