Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 7/20 | 0.32 |
| ▸ | HTR2B | P41595 | 7/20 | 0.32 |
| ▸ | HTR2A | P28223 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732573 | 0.87 | PTPN1 (0.38) | PTPN1HTR2CHTR2BHTR2A | |
| SCHEMBL3742273 | 0.86 | PTPN1 (0.36) | PTPN1HTR2CHTR2BHTR2A | |
| SCHEMBL3732060 | 0.84 | PTPN1 (0.52) | PTPN1HTR2CHTR2BHTR2A | |
| SCHEMBL4374699 | 0.84 | PTPN1 (0.44) | PTPN1HTR2CHTR2BHTR2A | |
| SCHEMBL4374731 | 0.83 | PTPN1 (0.54) | PTPN1HTR2B | |
| SCHEMBL3732360 | 0.82 | PTPN1 (0.45) | PTPN1HTR2CHTR2BHTR2A | |
| SCHEMBL4381212 | 0.82 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL4374330 | 0.81 | PTPN1 (0.42) | PTPN1HTR2CHTR2BHTR2A | |
| SCHEMBL4376462 | 0.81 | PTPN1 (0.42) | PTPN1HTR2CHTR2BHTR2A | |
| SCHEMBL4389725 | 0.81 | PTPN1 (0.43) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910359-B1 | PYRIDO [2 , 3-D]PYRIMIDINE-2 , 4-DIAMINE COMPOUNDS AS PTPlB INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-18 | — | — | EP | claimed |