SCHEMBL4380453

SCHEMBL4380453

CCCCC(CC)CCCCCN=C=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.42
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 4/20 0.41
USP2 O75604 3/20 0.41
MEN1 O00255 2/20 0.41
TP53 P04637 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP3A4 P08684 5/20 0.40
BCL2L1 Q07817 3/20 0.40
BAK1 Q16611 3/20 0.40
ALOX15 P16050 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29024394 0.98 CA2 (0.43) CA2ALDH1A1TDP1TSHRUSP2
SCHEMBL5507251 0.94 NAAA (0.34) CA2ALDH1A1TDP1TSHRUSP2
SCHEMBL28218348 0.91 NAAA (0.45) CA2TSHRUSP2MEN1TP53
SCHEMBL28287327 0.91 NAAA (0.45) CA2TSHRUSP2MEN1TP53
SCHEMBL28218302 0.91 NAAA (0.45) CA2TSHRUSP2MEN1TP53
SCHEMBL28218311 0.91 NAAA (0.45) CA2TSHRUSP2MEN1TP53
SCHEMBL11321426 0.89 NAAA (0.47) MEN1KMT2ALMNANAAAMAPT
SCHEMBL23709872 0.85 NAAA (0.35) CA2ALDH1A1TDP1TSHRUSP2
SCHEMBL28083969 0.85 USP2 (0.36) CA2ALDH1A1TDP1TSHRUSP2
SCHEMBL28285272 0.85 NAAA (0.38) LMNANAAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1423444-B9 AMPHOTERIC POLYMER RESINS THAT INCREASE THE RATE OF SIZING DEVELOPMENT HERCULES INC (US) 2009-11-18 EP disclosed
EP-1423444-B1 AMPHOTERIC POLYMER RESINS THAT INCREASE THE RATE OF SIZING DEVELOPMENT HERCULES INC (US) 2008-05-28 EP disclosed
CN-100343295-C Amphoteric polymer resins that increase the rate of sizing development HERCULES INC (US) 2007-10-17 CN disclosed
US-7270727-B2 Retention of brightness due to added optical brighteners HERCULES INCORPORATED (US) 2007-09-18 US disclosed
CN-1610708-A Amphoteric polymer resins that increase the rate of sizing development HERCULES INC (US) 2005-04-27 CN disclosed
EP-1423444-A1 AMPHOTERIC POLYMER RESINS THAT INCREASE THE RATE OF SIZING DEVELOPMENT HERCULES INCORPORATED (US) 2004-06-02 EP disclosed
US-20040016528-A1 Paper sized with a sizing agent and a selected sizing promoter BIRKO CORPORATION 2004-01-29 US disclosed
US-20030127204-A1 Amphoteric polymer resins that increase the rate of sizing development HERCULES CORPORATION 2003-07-10 US disclosed
WO-2003022898-A1 AMPHOTERIC POLYMER RESINS THAT INCREASE THE RATE OF SIZING DEVELOPMENT HERCULES INCORPORATED (US) 2003-03-20 WO disclosed
US-5853542-A Method of sizing paper using a sizing agent and a polymeric enhancer and paper produced thereof HERCULES INCORPORATED (US) 1998-12-29 US disclosed
EP-0074544-B2 AQUEOUS SIZING COMPOSITIONS HERCULES INCORPORATED (US) 1991-12-27 EP disclosed
EP-0074544-B1 AQUEOUS SIZING COMPOSITIONS HERCULES INCORPORATED (US) 1986-11-05 EP disclosed
US-4522686-A KETENE DIMER, ROSIN AND NITROGEN CONTAIN CATIONIC DISPERSANT HERCULES INCORPORATED (US) 1985-06-11 US disclosed
EP-0074544-A1 Aqueous sizing compositions HERCULES INCORPORATED (US) 1983-03-23 EP disclosed
US-4317756-A Sizing composition comprising a hydrophobic cellulose-reactive sizing agent and a cationic polymer HERCULES INCORPORATED (US) 1982-03-02 US disclosed
US-4295931-A POLYDIALLYLAMINE-EPIHALOHYDRIN RESIN, KETENE DIMER OR ANHYDRIDE OR ISOCYANATE, PAPER HERCULES INCORPORATED (US) 1981-10-20 US disclosed
US-4279794-A FOR PAPER, USING A KETENE DIMER SIZING AGENT AND A POLY(DIALLYLAMINE) EPIHALOHYDRIN RESIN AS ACCELERATOR HERCULES INCORPORATED (US) 1981-07-21 US disclosed
US-4243481-A PAPER REACTIVE SIZE, ANHYDRIDES, KETENE DIMER, ISOCYANATES; CATIONIC POLYMER PROMOTERS HERCULES INCORPORATED (US) 1981-01-06 US disclosed