Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14149334 | 0.85 | KCNK3 (0.45) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL13615128 | 0.84 | TYK2 (0.47) | MAPK1MCL1OGG1MAPTALDH1A1 | |
| SCHEMBL11095814 | 0.84 | ALDH1A1 (0.39) | MAPK1MCL1OGG1MAPTKMT2A | |
| SCHEMBL4387162 | 0.84 | KDR (0.38) | MAPK1MCL1OGG1MAPTKMT2A | |
| SCHEMBL10167644 | 0.77 | KMT2A (0.48) | MAPK1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL10167657 | 0.74 | LMNA (0.51) | — | |
| SCHEMBL10167653 | 0.73 | TRPV1 (0.42) | — | |
| SCHEMBL10167667 | 0.73 | SMO (0.44) | — | |
| SCHEMBL10167640 | 0.72 | NPC1 (0.47) | MAPTALDH1A1ROCK2CSF1RKDR | |
| SCHEMBL3810911 | 0.72 | PARP1 (0.39) | MAPK1MCL1OGG1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |