SCHEMBL4380987

SCHEMBL4380987

O=C(Cl)C1CC(C(=O)Cl)C1

nearest known ligand 0.30

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.30
LMNA P02545 2/20 0.30
BLM P54132 2/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30
PMP22 Q01453 1/20 0.30
KMT2A Q03164 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890411 1.00 CYP2D6 (0.30) CYP2D6LMNABLMALOX15TSHR
SCHEMBL27340865 1.00 CYP2D6 (0.30) CYP2D6LMNABLMALOX15TSHR
SCHEMBL524795 1.00 CYP2D6 (0.30) CYP2D6LMNABLMALOX15TSHR
SCHEMBL14829522 0.87 CYP2C19 (0.41) CYP2D6LMNABLMALOX15TSHR
SCHEMBL14829268 0.87 CYP2C19 (0.41) CYP2D6LMNABLMALOX15TSHR
SCHEMBL2154406 0.85 ACE (0.36) LMNACES2CES1
SCHEMBL11820398 0.85
SCHEMBL11819070 0.82
SCHEMBL3795815 0.82 GABRR1 (0.30)
SCHEMBL4029521 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119971800-A High-stability anti-pollution efficient composite reverse osmosis membrane and preparation method thereof 中国矿业大学(北京) 2025-05-13 CN claimed
CN-117534834-A Polymer, preparation method and application thereof, and intrinsic low-temperature curing negative photoresist 上海交通大学 2024-02-09 CN claimed
CN-119971800-A High-stability anti-pollution efficient composite reverse osmosis membrane and preparation method thereof 中国矿业大学(北京) 2025-05-13 CN disclosed
CN-117534834-A Polymer, preparation method and application thereof, and intrinsic low-temperature curing negative photoresist 上海交通大学 2024-02-09 CN disclosed
CN-116802774-A Hollow microsphere 株式会社德山 2023-09-22 CN disclosed
CN-115220305-A Positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-10-21 CN disclosed
EP-1116751-B1 POLYCARBONATE RESIN COMPOSITION, OPTICAL RECORDING MEDIUM, AND SUBSTRATE THEREFOR TEIJIN LTD (JP) 2009-07-29 EP disclosed
EP-1191064-B1 AROMATIC POLYCARBONATE COMPOSITION TEIJIN LTD (JP) 2005-12-07 EP disclosed
US-6448365-B1 Aromatic polycarbonate composition TEIJIN LIMITED (JP) 2002-09-10 US disclosed
US-6423813-B1 FROM PHENOLIC COMPOUNDS TEIJIN LIMITED (JP) 2002-07-23 US disclosed
US-6407199-B1 MIXTURE OF AROMATIC POLYCARBONATE AND CYCLIC CARBONATE COMPOUND; HEAT RESISTANCE TEIJIN LIMITED (JP) 2002-06-18 US disclosed
EP-1179556-A1 BRANCHED AROMATIC POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND BLOW-MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2002-02-13 EP disclosed
US-6300459-B1 TRANSESTERIFYING AROMATIC POLYCARBONATE AND ACTIVE-HYDROGEN COMPOUND UNDER REDUCED PRESSURE FOLLOWED BY REACTION WITH SPECIFIED SALICYLIC ESTER DERIVATIVE TEIJIN LIMITED (JP) 2001-10-09 US disclosed
EP-1116751-A1 POLYCARBONATE RESIN COMPOSITION, OPTICAL RECORDING MEDIUM, AND SUBSTRATE THEREFOR TEIJIN LIMITED (JP) 2001-07-18 EP disclosed
EP-0982340-A1 PROCESS FOR PRODUCING AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-01 EP disclosed
EP-0736561-A2 Dihydroxy compound mixtures and polymers thereof GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
EP-0277376-B1 AROMATIC AMIDE GROUPS-CONTAINING DIAMINES AND POLYMERS IN WHICH THESE DIAMINES ARE INCORPORATED AKZO N.V. (NL) 1991-02-27 EP disclosed
US-4980444-A Polyamides, polyureas, polyimides; heat resistance, melt processability, high strength fibers, films AKZO N.V. (NL) 1990-12-25 US disclosed
US-4851562-A HEAT RESISTANCE, MELT PROCESS ABILITY AKZO N.V. (NL) 1989-07-25 US disclosed
US-4511709-A Wholly aromatic or aliphatic aromatic block copolyamides and process therefor KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1985-04-16 US disclosed