SCHEMBL2154406

SCHEMBL2154406

O=C(Cl)C1CCC(C(=O)Cl)C1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.36
CHRNB2 P17787 4/20 0.35
CHRNA3 P32297 4/20 0.35
CHRNA4 P43681 4/20 0.35
CHRNB4 P30926 3/20 0.35
CHRNA7 P36544 2/20 0.35
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
CHRNB3 Q05901 1/20 0.33
CHRNA6 Q15825 1/20 0.33
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HPGD P15428 1/20 0.32
PLG P00747 1/20 0.31
PLAT P00750 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
AKR1C3 P42330 1/20 0.30
AKR1C1 Q04828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4279 0.89
SCHEMBL1506461 0.89 CHRNB2 (0.36) ACECHRNB2CHRNA3CHRNA4CHRNB4
SCHEMBL1060400 0.89 CHRNB2 (0.36) ACECHRNB2CHRNA3CHRNA4CHRNB4
SCHEMBL890380 0.89 CHRNB2 (0.36) ACECHRNB2CHRNA3CHRNA4CHRNB4
SCHEMBL14829469 0.88 ACE (0.50) ACEPLGPLATLMNAAKR1C3
SCHEMBL16941963 0.87 CES2 (0.43) CHRNB2CHRNA3CHRNA4CES2CES1
SCHEMBL890370 0.87 CES2 (0.43) CHRNB2CHRNA3CHRNA4CES2CES1
Hydrochloric Acid SCHEMBL1880027 0.86
SCHEMBL890411 0.85 CYP2D6 (0.30) CES2CES1LMNA
SCHEMBL4380987 0.85 CYP2D6 (0.30) CES2CES1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025128332-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
WO-2025128333-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
WO-2025128334-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
US-20250189892-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 US disclosed
US-20250188311-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 US disclosed
US-20250188312-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 US disclosed
CN-116802774-A Hollow microsphere 株式会社德山 2023-09-22 CN disclosed
EP-3119199-B1 COMPOUNDS AND THEIR METHODS OF USE AGIOS PHARMACEUTICALS INC (US) 2020-03-18 EP disclosed
EP-3184171-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-20 EP disclosed
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-12-04 US disclosed
EP-1191064-B1 AROMATIC POLYCARBONATE COMPOSITION TEIJIN LTD (JP) 2005-12-07 EP disclosed
US-6448365-B1 Aromatic polycarbonate composition TEIJIN LIMITED (JP) 2002-09-10 US disclosed
US-6423813-B1 FROM PHENOLIC COMPOUNDS TEIJIN LIMITED (JP) 2002-07-23 US disclosed
US-6407199-B1 MIXTURE OF AROMATIC POLYCARBONATE AND CYCLIC CARBONATE COMPOUND; HEAT RESISTANCE TEIJIN LIMITED (JP) 2002-06-18 US disclosed
EP-1191064-A1 AROMATIC POLYCARBONATE COMPOSITION TEIJIN LIMITED (JP) 2002-03-27 EP disclosed
EP-1179556-A1 BRANCHED AROMATIC POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND BLOW-MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2002-02-13 EP disclosed
US-6300459-B1 TRANSESTERIFYING AROMATIC POLYCARBONATE AND ACTIVE-HYDROGEN COMPOUND UNDER REDUCED PRESSURE FOLLOWED BY REACTION WITH SPECIFIED SALICYLIC ESTER DERIVATIVE TEIJIN LIMITED (JP) 2001-10-09 US disclosed
EP-1116751-A1 POLYCARBONATE RESIN COMPOSITION, OPTICAL RECORDING MEDIUM, AND SUBSTRATE THEREFOR TEIJIN LIMITED (JP) 2001-07-18 EP disclosed
EP-0982340-A1 PROCESS FOR PRODUCING AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-01 EP disclosed
EP-0736561-A2 Dihydroxy compound mixtures and polymers thereof GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins NIT2, NCLN, NPM1 ACE 1465/4885CHRNB2 4031/4885CHRNA3 3912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.