SCHEMBL890411

SCHEMBL890411

O=C(Cl)C1C[C@H](C(=O)Cl)C[C@H](C(=O)Cl)C1

nearest known ligand 0.30

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.30
LMNA P02545 2/20 0.30
BLM P54132 2/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30
PMP22 Q01453 1/20 0.30
KMT2A Q03164 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4380987 1.00 CYP2D6 (0.30) CYP2D6LMNABLMALOX15TSHR
SCHEMBL27340865 1.00 CYP2D6 (0.30) CYP2D6LMNABLMALOX15TSHR
SCHEMBL524795 1.00 CYP2D6 (0.30) CYP2D6LMNABLMALOX15TSHR
SCHEMBL14829522 0.87 CYP2C19 (0.41) CYP2D6LMNABLMALOX15TSHR
SCHEMBL14829268 0.87 CYP2C19 (0.41) CYP2D6LMNABLMALOX15TSHR
SCHEMBL2154406 0.85 ACE (0.36) LMNACES2CES1
SCHEMBL11820398 0.85
SCHEMBL11819070 0.82
SCHEMBL3795815 0.82 GABRR1 (0.30)
SCHEMBL4029521 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2024-10-10 US disclosed
US-12036515-B2 Thin-film composite membrane and methods of making and using the same THE PENN STATE RESEARCH FOUNDATION (PA) 2024-07-16 US disclosed
US-20210370240-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2021-12-02 US disclosed
EP-2788108-A1 MEMBRANE, WATER TREATMENT SYSTEM, AND METHOD OF MAKING General Electric Company (US) 2014-10-15 EP disclosed
US-8716472-B2 Tripodal cyclohexane derivatives and their use as carbohydrate receptors UNIVERSITY OF ROCHESTER (US) 2014-05-06 US disclosed
US-8591741-B2 Thin film composite membranes incorporating carbon nanotubes GENERAL ELECTRIC COMPANY (US) 2013-11-26 US disclosed
WO-2013085657-A1 MEMBRANE, WATER TREATMENT SYSTEM, AND METHOD OF MAKING GENERAL ELECTRIC COMPANY (US) 2013-06-13 WO disclosed
US-20130146530-A1 MEMBRANE, WATER TREATMENT SYSTEM, AND METHOD OF MAKING GENERAL ELECTRIC COMPANY (US) 2013-06-13 US disclosed
US-20120080381-A1 THIN FILM COMPOSITE MEMBRANES INCORPORATING CARBON NANOTUBES GENERAL ELECTRIC COMPANY (US) 2012-04-05 US disclosed
US-20120080380-A1 THIN FILM COMPOSITE MEMBRANES INCORPORATING CARBON NANOTUBES GENERAL ELECTRIC COMPANY (US) 2012-04-05 US disclosed
US-20050272677-A1 Delivery of a substance to a pre-determined site APPLIED NANOSYSTEMS B.V. (NL) 2005-12-08 US disclosed
US-20050250857-A1 Gelling agents NANO FIBER MATRICES B.V. (NL) 2005-11-10 US disclosed
EP-1506168-A2 GELLING AGENTS Applied NanoSystems B.V. (NL) 2005-02-16 EP disclosed
EP-1490028-A1 DELIVERY OF A SUBSTANCE TO A PRE-DETERMINED SITE Applied NanoSystems B.V. (NL) 2004-12-29 EP disclosed
WO-2003097587-A2 GELLING AGENTS APPLIED NANOSYSTEMS B.V. (NL) 2003-11-27 WO disclosed
EP-1364941-A1 Gelling agents Applied NanoSystems B.V. (NL) 2003-11-26 EP disclosed
WO-2003084508-A1 DELIVERY OF A SUBSTANCE TO A PRE-DETERMINED SITE APPLIED NANOSYSTEMS B.V. (NL) 2003-10-16 WO disclosed
US-5616249-A USING ALL ALIPHATIC POLYAMIDES FROM POLYAMINO COMPOUNDS AND COMPOUNDS HAVING TWO OR MORE ACID HALIDE GROUPS IONICS, INCORPORATED (US) 1997-04-01 US disclosed
EP-0587610-A1 SPECIFICALLY BETA-BETA CROSS-LINKED HEMOGLOBINS AND METHOD OF PREPARATION THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) 1994-03-23 EP disclosed
US-5250665-A Artificial blood THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) 1993-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050272677-A1 Delivery of a substance to a pre-determined site TACR1, TACR2, NPSR1 CYP2D6 472/4885LMNA 238/4885BLM 4382/4885
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 CYP2D6 3627/4885LMNA 356/4885BLM 654/4885
US-12036515-B2 Thin-film composite membrane and methods of making and using the same PORCN, MLEC, FLOT1 CYP2D6 3627/4885LMNA 356/4885BLM 654/4885
US-20210370240-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 CYP2D6 3627/4885LMNA 356/4885BLM 654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.