Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | NCF1 | P14598 | 1/20 | 0.59 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GNG2 | P59768 | 2/20 | 0.49 |
| ▸ | GNB1 | P62873 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440491 | 0.85 | NR4A2 (0.74) | NR4A2POLBNCF1KMT2AGNG2 | |
| SCHEMBL1147963 | 0.81 | NR4A2 (0.68) | NR4A2POLBSOS2KMT2AMPO | |
| SCHEMBL6492060 | 0.81 | POLB (1.00) | NR4A2POLBKMT2AMPOBCHE | |
| SCHEMBL4745343 | 0.81 | POLB (0.72) | NR4A2POLBKMT2AMPOBCHE | |
| SCHEMBL6492059 | 0.78 | POLB (0.68) | NR4A2POLBKMT2AMPOBCHE | |
| SCHEMBL30682591 | 0.78 | NR4A2 (0.64) | NR4A2POLBNCF1KMT2AGNG2 | |
| SCHEMBL442339 | 0.78 | NR4A2 (0.64) | NR4A2POLBNCF1KMT2AGNG2 | |
| SCHEMBL4744795 | 0.78 | POLB (0.68) | NR4A2POLBKMT2AMPOALDH1A1 | |
| SCHEMBL442241 | 0.78 | NR4A2 (0.64) | NR4A2POLBNCF1KMT2AGNG2 | |
| SCHEMBL439508 | 0.77 | NR4A2 (0.62) | NR4A2POLBNCF1KMT2AGNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |